The NIHR, Invention for Innovation i4i and Future Product Development

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The NIHR, Invention for Innovation (i4i) and
Future Product Development

• Dr Richard Curry
• Senior Scientific Advisor, DH RD Directorate

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The central role of NIHR research in the
innovation pathway
CREATE
REFINE
EVALUATE
USE
APPRAISE
Basic Research
MRC
Development Pathway Funding
Invention for Innovation
Biomedical Research Centres
This pathway covers the full range of
interventions - pharmaceuticals, biologicals,
biotechnologies, procedures, therapies and
practices - for the full range of health and
health care delivery - prevention, detection,
diagnosis, prognosis, treatment, care.
Biomedical Research Units
Patient Safety and QualityResearch Centres
Research for Innovation,Speculation Creativity
Research for Patient Benefit
Health Services Research
Programme Grants forApplied Research
National Institutefor Health Research
Public Health Research
Service Delivery Organisation
Health Technology Assessment
Centre for Reviews Dissemination, Cochrane, TARs
Collaborations for Leadershipin Applied Health
Research and Care
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• The aim of Invention for Innovation (i4i) is to
  improve the identification of innovative
  healthcare technologies and accelerate the
  development of new healthcare products for the
  21st century.

Remit of i4i
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• i4i Invention for Innovation

i4i
Secretariat Advisory group
SBRI Requirement led development
FPD Investigator led development
HTC CFI Links to ideas generators
exploiters
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• Small Business Research Initiative (SBRI)
• The aim of SBRI is to use government procurement
  to drive technology development, through
  competitive tendering especially in early-stage
  companies.
• First call in HCAI opened Oct 08 closed Nov.
  Contracts being placed for phase 1 now.

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• Healthcare Technology Co-operatives
• Virtual organisation which will bring together a
  wide spectrum of stakeholders with a common
  purpose.
• Bowel Function HTC
• Devices for Dignity HTC
• i4i ideas generators

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• Challenge Fund for Innovation (CFI)
• Supporting partner programmes
• MATCH EPSRC
• ALIP KTP TSB
• Medical Futures - Private

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Future Product Development (FPD)

• 1. Future Product Development Stream 1 (FPD1)
  Feasibility study
• Up to 1 year, clinician or academic led, to study
  if prior basic research can be used to meet a
  healthcare need, funding 100K maximum is
  available.
• 2. Future Product Development Stream 2 (FPD2)
  Applied research project
• Detailed 2-3 year investigation, clinician or
  academic led, to provide further evidence of the
  capability to deliver improved healthcare
  outcomes, funding 150K-250K per year is
  available.
• Future Product Development Stream 3 (FPD3)
• a) Commercial Viability Study Up to one year,
  collaborative, to study innovative use of an
  existing or emerging product or technology to
  meet a healthcare need. First stage of a full
  collaborative applied research project, 75
  funding 100K typically available.
• b) Collaborative applied research Detailed 2-3
  year investigation, collaborative between
  industrial and research partners, to demonstrate
  the delivery of improved healthcare outcomes, 50
  funding 300K per year is typically available.

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i4i Activity
SBRI (ii)
SBRI (i)
HTCs
Research Councils
Funding Stream 3
Funding Stream 1
Funding Stream 2
Private Investment
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Assessment of proposals

• The same criteria are used to assess proposals to
  each of the three streams
• Scientific and technical quality
• Clinical or healthcare need
• Market potential
• Freedom to operate
• Arrangements for protecting IP generated
• Project team quality
• Project plan quality
• Involvement of users and industry
• Justification of resources

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Benefits of FPD

• The FPD programme has been designed to offer
  investigators
• Flexibility of entry points dependent on the
  maturity of the idea investigators can apply for
  funding from any of the three streams and if
  appropriate proceed from stream to stream.
• Co-ordination between streams through having the
  one secretariat.
• Support to projects that meet their milestones
  and show promise so that they can move onto the
  next funding stream with the minimum of delay and
  are accelerated along the innovation pathway.
• A rolling programme of calls for proposals to
  better fit with the innovation process

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Project Support

• Project support consists of
• Project monitoring
• Exploitation advice

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Secretariat

• Dr. Richard Curry
• Debbie Romney- Alexander
• Dr. Martin Anyim
• Dr. Belinda Haupt
• Miriam Piterkova
• Andrew Davidson
• Charlotte Green
• Matthew Chapman

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Websites and email

• For further information and forms
• www.nihr-ccf.org.uk/site/programmes/i4i
• Transforming Health Research
• www.nihr.ac.uk/publications.aspx
• Richard Curry
• rcurry_at_netcomuk.co.uk