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T32 Training Program in the Biology of Cancer

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T32 Training Program in the Biology of Cancer Larry H. Matherly, Ph.D. Director, Cancer Biology Graduate Program Department of Oncology November 15, 2012 – PowerPoint PPT presentation

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Title: T32 Training Program in the Biology of Cancer


1
T32 Training Program in the Biology of Cancer
  • Larry H. Matherly, Ph.D.
  • Director, Cancer Biology Graduate Program
  • Department of Oncology
  • November 15, 2012

2
Cancer Biology Graduate Program
  • Provides foundation for T32 CA009531
  • Founded in 1987
  • Based in the Department of Oncology (2010) at WSU
  • Broad-based curriculum in state-of-the-art
    molecular and cell biology research with strong
    specialization in cancer
  • Unique interface of graduate program with
    clinical activities in the KCI cancer hospital

Shermaine Mitchell-Ryan (Y4)
3
Cancer Biology Graduate Program
  • Currently 57 interdisciplinary faculty
  • Areas of research interest broadly include tumor
    biology, tumor immunology, cancer prevention,
    carcinogenesis, cancer therapeutics, molecular
    genetics, population studies, and cancer
    metatasis

Seema Shah (Y3)
4
Cancer Biology Graduate Program
  • 30 trainees
  • 29 domestic trainees
  • 12 males, 18 females
  • 2 MD/PhD trainees
  • 5 URM trainees
  • 4-5 recruits per year
  • 4 trainees currently supported by F30/F31
    fellowships
  • gt97 completion rate
  • 4.7 years to completion

Aaron Burr (Y3)
5
Cancer Biology Graduate Program
  • More than 70 PhD alumni have progressed to
    postdoctoral training positions in universities,
    research institutes, and pharmaceutical firms
  • At least twelve hold academic rank of at least
    Assistant Professor
  • Many others in pharma, other professional
    positions

Dr. Johnathan Whetstine, Dr. Matherly, and Dr.
Jeffrey Taub
6
T32 CA009531-26
  • Training in the Biology of Cancer
  • Currently in year 26
  • Last competitive review in February 2012
  • Received perfect score of 10
  • Renewed for years 26-30
  • 19 faculty members
  • 2 junior faculty, 2 clinical faculty
  • Supports 6 predoctoral trainees/year
  • Draws from Departments of Oncology and
    Pharmacology

7
T32 Stategies
  • Focus of training program
  • Interdisciplinary, topical, unique niche
  • Pre- and postdoctoral trainees
  • Relation to other training programs
  • Pre- and postdoctoral training grants (e.g., R25,
    T32)
  • Other support mechanisms (GRAs, individual
    F31-type fellowships)
  • Benefits to trainees
  • Separate from other departmental/institutional
    programs

8
Game plan for T32
  • Program director should have active extramurally
    supported research program
  • Experience in education, administration, and
    mentorship
  • Associate Director with similar qualifications
  • Internal and external advisory committees

9
Game plan for T32
  • Diverse, well funded, generally experienced
    mentors
  • Include faculty of different ranks
  • May require co-mentors
  • Evidence of faculty collaboration
  • Documented training history (trainee
    publications, grants, professional appointments,
    etc.)
  • Evaluative process for mentor selection and
    replacement

10
Game plan for T32
  • Robust applicant pool (highly selective)
  • Domestic (training grant eligible)
  • Not all local
  • 5 year history of applicant numbers (applied,
    enrolled, completed degree)
  • Qualifications of most recent applicant pool and
    current trainees (institution, GPA, GREs)
  • MD/PhD trainees
  • Good recruitment strategies
  • Graduate fairs
  • Undergraduate research fellowships
  • Recruiting day
  • Strong discriminators of success

11
Game plan for T32
  • Diversity recruitment
  • Track record on recruitment and retention
  • Specific recruiting plan
  • ABRCMS
  • Partner with minority institutions
  • Alumni
  • IMSD
  • Deans Diversity Fellowship
  • Summer undergraduate programs
  • Must justify number of training slots
  • Particular focus (e.g., MD/PhD)

12
Game plan for T32
  • Robust trainee selection criterion
  • Nomination and competition
  • Ratio of nominees/trainees
  • For predocs, no support for first year
  • Distribution of trainees to mentors
  • Retention and graduation rates
  • 100 of training slots filled
  • Focus on underrepresented minorities
  • Plan to evaluate trainee progress
  • Annual review (2 year max support)
  • Exit interview

13
Game plan for T32
  • Must document training facilities, key equipment,
    and types of departmental or interdepartmental
    interactions among trainees and faculty
  • Plans to address issues of institutional
    geography and trainee access to scientific,
    educational, and clinical resources

14
Game plan for T32
  • Must provide evidence of institutional support
  • Cost sharing, tuition/benefit coverage
  • No faculty salaries allowed
  • 40 tuition costs not covered for predocs
  • Insurances exceeding 2000 not covered
  • Stipend and tuition support for years prior to
    and following T32 support
  • Infrastructure (facilities, cores, specimens,
    grants management, purchasing, etc.)
  • Other support (program staff, recruiting costs,
    travel to scientific conferences, etc.)
  • Documentation is essential

15
Game plan for T32
  • Unique features of training plan
  • Unique curriculum (e.g., didactic courses,
    clinical rounding, qualifying exams, etc.)
  • Other training opportunies (networking, symposia,
    seminars, etc.)
  • National/international meetings, special
    workshops, local meetings (GSRD, Graduate Student
    Forum), etc.
  • Clinical interface
  • Transition to individual fellowships
  • Practical training (traditional/non-traditional,
    grant and fellowships, lab management, etc.)
  • Special populations (women, minorities)

16
Game plan for T32
  • Responsible conduct of research
  • Mandatory
  • Didactic course
  • Documented curriculum
  • Participating faculty
  • Record of participation

17
Game plan for T32
  • Trainees must continue to be productive in field
    and advance up professional ladder
  • 10 year follow-up (professional appointments,
    publications, grants, honors)
  • Evidence of career progression
  • Open to interpretation
  • Publications, grants, honors, positions, etc.
  • Plan for trainee follow-up
  • Tracking and solicitation
  • Alumni visits

18
Game plan for T32
  • Effect of training program on curriculum and/or
    research orientation
  • Impact on faculty productivity
  • Foster collaborations
  • Institutional visibility
  • Faculty and trainee recruiting
  • Value of training-related expenses
  • Training costs
  • Travel and professional development
  • Special programs

19
Questions?
CB Graduate Students with Dr. Judith
Campisi Cancer Biology Student Symposium, May 2012
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