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Endocrine Pathology

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Overview Pathologies Diabetes Mellitus Separate Lecture Disorders of the Pituitary Gland Disorders of the Thyroid & Parathyroid Disorders of the Adrenals ... – PowerPoint PPT presentation

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Title: Endocrine Pathology


1
Endocrine Pathology
2
Overview Pathologies
  • Diabetes Mellitus Separate Lecture
  • Disorders of the Pituitary Gland
  • Disorders of the Thyroid Parathyroid
  • Disorders of the Adrenals
  • Thermoregulation and Environmental Conditions
  • Metabolic Disorders

3
Introduction Endocrine System
  • Maintain equilibrium
  • Regulate functions of organ systems, through
    hormones
  • Reproductive
  • Growth Development
  • Defense against stressors
  • Blood Glucose levels
  • Core body Temp
  • Water electrolyte balance
  • Metabolism

4
Anatomy
5
Anatomy
6
Glands
  • Hypothalamus-
  • Pituitary Gland-
  • Thyroid-
  • Parathyroid-
  • Adrenal Glands-
  • Pancreas-
  • Ovaries/Testes-

7
Body Function Regulation
  • Body Energy
  • Body Temperature
  • Body Fluid
  • Hormone response to Exercise

8
Common Signs Symptoms
  • Skin changes
  • Diaphoresis hyperhydrosis
  • Body or Breath Odor
  • Polydipsia or Polyuria
  • Arthralgia Myalgia
  • Muscle Atropy weakness
  • Amenorrhea Impotence
  • Mental Status changes
  • Paresthesia
  • Edema
  • Polyphagia
  • Orthostatic Hypotension
  • Lethargy/Fatigue
  • Pain Patterns

9
Disorders of the Pituitary Gland
  • Diabetes Insipidus
  • Acromegaly

10
Disorders of the Thyroid
  • Hyperthyroidism
  • Graves Disease

11
Disorders of the Thyroid
  • Hypothyroidism

12
Disorders of the Adrenals
  • Addisons Disease
  • Cushings Syndrome

13
Thermoregulation/Environmental
  • Heat Cramps
  • Heat Syncope
  • Heat Exhaustion
  • Heat Stroke
  • Exertional Hyponatremia
  • Frostbite
  • Hypothermia
  • Altitude Sickness

14
Metabolic Disorders
  • Gout
  • Metabolic Bone Disease
  • Osteoporosis
  • Paget Disease

15
The Tired Athlete
  • Psychological Profile of Athletes Separate
    Lecture
  • Endocrine Disorders
  • Infections
  • Anemia
  • Iron Deficiency Anemia
  • Dilutional Pseudo-Anemia

16
Im Still Tired
  • Infections
  • 1.
  • 2.
  • 3.
  • 4.

17
Still Tired
  • Anemia
  • Fatigue usually c exertion
  • Lack of RBC
  • Most commonly iron-deficiency
  • Reduction of red cell mass or blood hemoglobin
    concentration

18
Classification of Anemia
  • 1. Cell Proliferation
  • A.
  • B.
  • 2. Maturation
  • 3. Destruction

19
Ineffective Erythropoiesis
  • Iron deficiency
  • Vitamin B12 deficiency
  • Folic acid deficiency

20
Anemia
  • Think about elevation
  • S/S
  • At Risk Population

21
Laboratory Finding
  • Hct ()
  • women 36-48 men 40-52
  • Hb (g/dl) Normal is 12-16
  • Anemic when lt 12 g/dl
  • MCV Normal is 80-100
  • 60-70 Micro 100 Macro
  • RBC count
  • women 4.0-5.4 men 4.5-6.0
  • Anemia small RBC c low ferritin

22
Iron Deficiency Anemia - Treatment
  • 3-6 mg per kg of body weight of elemental iron
  • Better with vitamin C on an empty stomach
  • Frequent monitoring

23
Iron Deficiency in Patients
  • Other causes Chronic Blood Loss

24
Sports Anemia
  • Dilutional pseudoanemia
  • Will not respond to tx
  • Normal MCV ferritin
  • No affect of performance

25
How to Assess Patients
  • HISTORY, HISTORY, HISTORY
  • Cover all organ systems
  • Physical Exam General Affect
  • Labs
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