Considering Honours in the Neuroendocrinology Research Group?

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Considering Honours in the Neuroendocrinology
Research Group?
The Neuroendocrinology Research Group provides a
diverse range of projects embracing three main
areas of research
The Tilbrook Lab.Impact of Stress on
Physiological Systems (click here)
The Nichols Lab.Endocrine Control of Adult
Neurogenesis (click here)
The Clarke Lab.Regulation of Reproduction (click
here)
Contact us
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Visceral Fat
Reproduction
Sex
How does stress impact on fertility? How does
reproductive experience affect learning and
memory in the face of a stressor?
Does being lean make you less responsive to
stress? Does being obese from an early age make
you more susceptible to disease?
Why do males and females have different
incidences of stress-related diseases?
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Endocrine Control of Adult Neurogenesis

• The Nichols lab is interested in regulation of
  adult neural stem cells by hormones and growth
  factors or cytokines
• We use both in vivo (upper panel brown cluster
  of proliferating nuclei) and in vitro approaches
  (lower panel blue nuclei, red neurons, green
  glia) to study how neural stem cells develop into
  functional neurons
• We are particularly interested in effects of
  stress and stress hormones (glucocorticoids) on
  neurogenesis during brain repair

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Regulation of Reproduction
Professor Iain Clarke has built an
internationally recognized group that has
remained consistently competitive in the field of
neuroendocrinology and brain mechanisms relevant
to the control of reproduction. Most recently,
his laboratory has made a major impact in the
field of kisspeptin and their imperative role in
regulating the GnRH system.
Expression of KiSS-1 mRNA in the Arcuate Nucleus
of the ewe. Detected by in situ hybridisation.
Projects Available

• Activation of the GnRH system by melanocortin
  agonists.

• Processing of POMC peptides in the arcuate
  nucleus in different physiological states and the
  effects of leptin.

• Role of Kisspeptin in the regulation of the GnRH
  system.

Immunohistochemisrty of Kisspeptin neurons (green
cells) co-expressing Progesterone Receptor (red
cells)in the Arcuate Nucleus.

• Effect of environmental pollutants and endocrine
  disruptors on the neuroendocrine systems.

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Contact Us
Professor Iain Clarke
Dr Nancy Nichols
Ass. Professor Alan Tilbrook
Department of Physiology Building 13F Room F228,
Clayton Campus Email iain.clarke_at_med.monash.e
du.au
Department of Physiology Building 13F Room F243,
Clayton Campus Email nancy.nichols_at_med.monash
.edu.au
Department of Physiology Building 13F Room F248,
Clayton Campus Email alan.tilbrook_at_med.monash
.edu.au
Back to Iains lab.
Back to Nancys lab.
Back to Alans lab.
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