From: Wolpert et al., Principles of Development

1
From Wolpert et al., Principles of Development
2
From Wolpert et al., Principles of Development
3
From Gilbert, Developmental Biology
Aristotle was rightjust wrong species
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From Moore Persaud, The Developing Human
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From Larsen, Human Embryology
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From Gilbert, Developmental Biology
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From Gilbert, Developmental Biology
Diagnostic Y-chromosome aberrations
Gray bars indicate DNA that is PRESENT
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From Gilbert, Developmental Biology
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SRY may be involved with RNA processing
red SRY Green SC-35 (an RNA processing
factor) Yellow overlap of expression
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Sox9 can induce testes formation
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(No Transcript)
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From Gilbert, Developmental Biology
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(No Transcript)
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From Gilbert, Developmental Biology
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From Gilbert, Developmental Biology
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From Wolpert et al., Principles of Development
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From Gilbert, Developmental Biology
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From Larsen, Human Embryology
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From Gilbert, Developmental Biology

• Androgen Insensitivity
• Syndrome
• XY karyotype
• internal testis
• female 2 sexual characteristics
• Almost always raised as females

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From Wolpert et al., Principles of Development
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MEDI 510 (IBS 518)

July 24
-
August 7, 2006



Human Embryology Development and Disease

Charles Saxe, Ph.D., Course Director



Text Moore, K.W., The Developing Human, W.B.
Saunders Co., 7th ed., 2003


Place
Week 1
lectures and clinical cor
relations will be in Whitehead Auditorium




Week 2
lectures and clinical correlations will be in
the WHSCAB Auditorium




Exams
all exams will be in the WHSCAB Auditorium




Day


Date


Time


Event


Speaker



Title



Mon

7/24

900a

Lect 1

Dr. Saxe

Basic mechanisms of differentiation




1100

Lect 2

Dr. Saxe

Morphogenesis and cell interactions




1145p

Corr


K. Torrente

Intro to information retrieval at











Emory



Tues

7/25

900

Lect 3

Dr. Saxe

Principles
of teratogenesis




1100

Lect 4

Dr. Saxe

Gametogenesis and fertilization




100p

Clin Corr

Dr. Mitchell Advances in
invitro
fertilization



Wed

7/26

900

Clin Corr

Ms Kinlaw

Neonatal ethics



1030

Lect 5

Dr. Saxe


Extra
-
embryoni
c membranes placenta



100p

Lect 6

Dr. Saxe

Urogenital system I. Gonads



Thur

7/27

900

Lect 7

Dr. Saxe


Urogenital system II. Renal development




1100

Clin Corr

Dr. Smith

Anomalies of the urinary tracts



Fri

7/28

900

Lect 8

Dr.
Moberg

Ectoderm
-
neurulation CNS formation





1045

Clin Corr

Dr. Sladky

Congenital Neural defects










Mon 7/31

900

MIDTERM

(1 hr)



Tues

8/1

900

Lect
9

Dr. Saxe

Cardiovasc I. Heart,CV system









Septation




1030 Lect 10 Dr. Saxe

Cardiovasc II. Congenital heart defects




1130

Clin Corr

Dr.Sutherland Common congenital heart defects



Wed

8/2

900

Lect 11 Dr. Saxe
Mesoderm I. limb and muscle mitotic










mechanisms




1030

Lect 12

Dr. Saxe

Mesoderm II. Limb and skeletal









formation





100p

Clin Corr

Dr. Weil

Congenital limb anomalies




Thur

8/3

900

Lect 13

Dr. Saxe

Endoderm I. Respiratory system




1030

Lect 14

Dr. Saxe

Endoderm II. Gut, Liver, Pancreas




100p

Clin Corr

Drs Nasr and Anomalies of the gut









Williams

Fri

8/4

900

Lect 15 Dr. Saxe

Cancer Developmental mecha
nisms








in oncogenesis













Mon

8/7

900

FINAL EXAM
(2 hr)