Q1' Prokaryotic cell E' coli consists of a single closedcircular DNA molecule of 4'6 x 106 bp long'

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Q1. Prokaryotic cell E. coli consists of a single
closed-circular DNA molecule of 4.6 x 106 bp
long. This DNA molecule would be 1.6 mm if the
double helix is relaxed. Please describe what
strategies does E. coli use to pack such a long
molecules into its nucleoid less than a
micrometer (mm) in diameter. (20 points) Q2.
Please list at least two different types of
proteins included in E. coli nucleoid, and
describe the biological function of these
proteins. (10points) Q3. Chromatin is the highly
ordered DNA-protein complex which makes up the
eukayotic chromosomes. gt50 of the mass is
protein