For Sale: smart, obedient, happy, tall, healthy, studious, helpful, and quiet children. Act now and receive a free glow in the dark plant

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For Sale smart, obedient, happy, tall, healthy,
studious, helpful, and quiet children.Act now
and receive a free glow in the dark plant
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DNA fingerprinting using RFLPs
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Visualizing differences in DNA sequence by using
restriction enzymes
Sequence 1
Sequence 2
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Restriction Enzymes cut DNA at specific sequences
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Examples of some restriction enzymes
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Visualizing differences in DNA sequence by using
restriction enzymes
Sequence 1
Sequence 2
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Separating DNA on a gel by size
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• Gel electrophoresis

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The different sized bands can arise from
different cut sites and/or different number of
nucleotides between the cut sites.
Sequence 1
Sequence 2
Sequence 1
Sequence 2
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DNA fingerprinting
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DNA fingerprinting
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DNA fingerprinting
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Computerized DNA sequencing is now inexpensive
and fast
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Genetic Engineering Direct manipulation of DNA
Fig 20.2
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We can now insert new genes or modify existing
genes of organisms
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In humans, viruses are used to insert DNA into
cells
gene
CB 20.22
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DNA can only be obtained from living cells.
No DNA
DNA in hair root
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dead cellsno DNA
From Biology N. Campbell et al (2005) Benjamin
Cummings fig 43.2
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Red blood cells do not have DNA, but white blood
cells do.
From Biology N. Campbell et al (2005) Benjamin
Cummings fig 42.13
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Humans have 25,000 genes in our genome spread
out over 3 billion nucleotides which produce
85,000 unique proteins
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Humans have 25,000 genes in our genome spread
out over 3 billion nucleotides which produce
85,000 unique proteins With so many genes, there
is almost no probability of finding an embryo
with "no major problems"?
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How close are we to picking our offspring?
Karyomapping is a new technique developed at a
British fertility clinic can test for 15,000
known genetic disorders. It takes DNA from
8-day-old in vitro fertilized embryos as well as
from the parents and possibly other
relatives.The test costs 2,300. http//news.bb
c.co.uk/2/hi/health/7688299.stm
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How close are we to picking our offspring?
the test could also be used, more
controversially, to detect a genetic profile
which showed a susceptibility to conditions such
as heart disease or cancer. http//news.bbc.co.u
k/2/hi/health/7688299.stm
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The material costs to sequence a complete human
genome are approaching 1,000 at a consumer cost
of 5,000
2001
2011
http//www.nature.com/news/2008/081006/full/news.2
008.1151.html and http//www.frontsidebus.net/2011
/03/costs-of-dna-sequencing-falling-fast-E28093
-look-at-these-graphs/
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Are hoodies a response to increased surveillance?
Targeting badly behaved Britons Mall bans
'hoodies' in latest effort to curb yob
culture http//www.msnbc.msn.com/id/7897532/
Photo Geoff Caddick / EPA via Sipa Press
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A first-class traveler cleared security with a
phony Twin Cities-to-Washington boarding pass for
Northwest Airlines, no photo identification and
wearing an Osama bin Laden T-shirt under his coat
as part of a test of airport security in this
post-9/11 world.http//www.startribune.com/lifest
yle/travel/minnesota/31275879.html
Security breaches are common
The Privacy Rights Clearinghouse reports 245
million sensitive records have been breached
since Jan. 2005 http//www.privacyrights.org/ar/C
hronDataBreaches.htmCP
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A species survival depends on maintaining genetic
diversityExtinction Vortex
From Biology N. Campbell et al (2005) Benjamin
Cummings fig 55.9
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Attwater Prairie Chicken As the population
declined, genetic diversity declined
From Biology N. Campbell et al (2005) Benjamin
Cummingsfig 55.10
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Attwater Prairie Chicken Individuals brought from
other populations increased reproduction and
population by increasing genetic diversity.
From Biology N. Campbell et al (2005) Benjamin
Cummingsfig 55.10
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What type of criteria are acceptable for
employment or admissions decisions? IQ, SAT,
MCAT, grades, extracurricular activities, drug
tests, letters of recommendation, personal
interview, essays
http//xkcd.com
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When does picking the best become choosing
traits?
Sex ratio in China, est. 2008 at birth 1.11
male(s)/female under 15 years 1.13
male(s)/female 15-64 years 1.06
male(s)/female Compare to U.S. at birth 1.05
male(s)/female http//www.indexmundi.com/china/dem
ographics_profile.html
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When does picking the best become choosing
traits?
What abnormality might a parent choose? One
study found that each inch above average may be
worth 789 more in salary per year. Journal of
Applied Psychology T. Judge and D. Cable (Vol.
89, No. 3).
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If everyone has faults, what faults are focused
on as critical and what faults are overlooked?
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How do we rein in technology once it is unleashed?
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How do we rein in technology once it is unleashed?
Global area planted with GM crops
Texas70ha
http//www.gmo-compass.org/eng/agri_biotechnology/
gmo_planting/257.global_gm_planting_2006.html And
http//www.monsanto.com.au/_images/global_area_cha
rt.gif
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How do fate, serendipity, and luck affect our
lives?
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Exam 3 in-class Optional Final Exam
For Sale smart, obedient, happy, tall, healthy,
studious, helpful, and quiet children.Act now
and receive a glow in the dark plant