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DNA Structure

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DNA Structure Forensics Chp. 12 DNA Analysis DNA Structure A gene is a long section of a DNA molecule whose sequence of building blocks specifies the sequence of ... – PowerPoint PPT presentation

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Title: DNA Structure


1
DNA Structure
  • Forensics
  • Chp. 12
  • DNA Analysis

2
DNA Structure
  • A gene is a long section of a DNA molecule whose
    sequence of building blocks specifies the
    sequence of amino acids in a particular protein.
  • Protein- fundamental component of living cells
  • Enzymes
  • Hormones
  • Antibodies
  • Hemoglobin
  • Insulin

3
How does DNA work
  • DNA (nucleic acid) ?
  • Amino Acids ?
  • Protein ? Do a job (perform a function)
  • Analogy to remember whats going on, build a
    house
  • DNA is the blue prints (instructions)
  • Amino Acids are the lumber
  • Proteins are the house

4
DNA Structure
  • View from the side - Helix
  • Partially unwound double helix so you can see
    components

5
Views from the top
Model
X-Ray
Photo-51
6
  • DNA composed of nucleotides
  • Sugar (deoxyribose)
  • Phosphate group
  • Nitrogenous bases
  • A - T
  • C - G

7
DNA Structure
  • A 5 C sugar and a phosphate group form the
    backbone

8
DNA Structure
  • Nitrogenous bases
  • A, T, C, G
  • make up the rungs on the ladder

9
Complimentary Base Pairing
  • Bases held together with Hydrogen bonds
  • Guanine pairs with Cytosine
  • Triple bond
  • Adenine pairs with Thymine
  • Double bond

10
DNA Structure
3D Video Clip (Click next 4 times)
11
3 methods to analyze DNA
  • RFLP- Restriction Fragment Lengths Polymorphism
  • Restriction enzymes cut DNA up
  • Not best method because we need a lot of DNA
  • PCR Polymerase Chain Reaction
  • Polymerase enzyme that replicates (makes more)
    DNA
  • STR Short Tandem Repeats
  • Specific sequences of DNA fragments that are
    repeated at a particular site on a chromosome

12
Replication Technology
  • Mitochondrial DNA- from mom only
  • good for hair, teeth, and bone
  • PCR-
  • Perhaps the most successful technology to ever
    emerge from LIFE SCIENCE!!!
  • Many Uses
  • Forensics-
  • blood, convict, exonerate false accusations
  • Agriculture, Vet., Medicine, Env. Sci.,
  • Microorganisms, viruses, parasites
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