Society for Gynecologic Investigation 51st Annual Meeting NIH Workshop: Research Opportunities for M

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Society for Gynecologic Investigation 51st Annual
MeetingNIH Workshop Research Opportunities for
Minority InvestigatorsMarch 24, 2004

• Estella C. Parrott, M.D., M.P.H.
• Reproductive Sciences Branch
• Center for Population Research
• NICHD, NIH, DHHS

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Reproductive Scientist Development Program (RSDP)

• Grant mechanism is the K12 Mentored Clinical
  Scientist Development Award (Institutional)
• Major Sponsor NICHD
• Candidates Completed residency training in
  obstetrics and gynecology
• All types of Ob/Gyn research
• Four slots per year
• Any top lab in the US
• Training divided into two Phases (Basic Science
  Development Phase and Independent Research Phase)
• Apply for seed grants year 1-2 and other funding
  years 3-5
• Candidates apply directly to program, not NIH
• Program Director Robert Jaffe, M.D., UCSF

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Womens Reproductive Health Research Career
Development Centers (WRHR)

• Grant mechanism is the K12 Mentored Clinical
  Scientist Development Award (Institutional)
• Major sponsor NICHD
• Cosponsors ORWH, NCI
• Mentored research experience for Ob/Gyn junior
  faculty leading to a career as an independent
  investigator
• 8 current Centers nationwide
• Spring 2004, 10 more WRHR Centers available to
  recruit Ob/Gyn candidates for research training
  and career development

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WRHR Centers Program Components

• Candidates Completed residency training in
  obstetrics and gynecology or subspecialty
  training
• Minimum of 3 Ob/Gyn scholars at each Center
• Rolling availability
• All types of Ob/Gyn research
• Research Projects basic, translational or
  clinical
• Candidates apply directly to the WRHR Center, not
  NIH
• At least 75 effort for up to 5 years

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Building Interdisciplinary Research Careers in
Womens Health (BIRCWH)

• Grant mechanism is the K12 Mentored Clinical
  Scientist Development Award (Institutional)
• Major sponsor ORWH
• Trans-NIH (8 Institutes/Offices) and AHRQ
• 24 current program sites
• Minimum of four scholars at each site
• Scholars may have a clinical doctorate or PhD
  degree
• All of womens health research eligible
• Candidates apply directly to program site, not
  NIH
• At least 75 effort for up to 5 years

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NIH Multidisciplinary Clinical Research Career
Development Program

• Trans-NIH Initiative
• Grant mechanism is the K12 Mentored Clinical
  Scientist Development Award (Institutional)
• Clinical research apprenticeship performed in
  mentored multidisciplinary team settings
• Integrate clinical research training across an
  institution
• Support career development of clinical
  researchers from a variety of disciplines
• Formal training in the discipline of clinical
  research
• Develop a national cadre of well trained clinical
  investigators

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NIH Multidisciplinary Clinical Research Career
Development Program

• Key features (at full implementation)
• 10 Training programs
• 20-25 Scholars per site
• Flexibility in effort
• At least 75 effort for up to 5 years
• Allow at least 50 effort for surgical
  specialties
• Core didactic courses, required the first year
• Tuition support for advanced degrees
• Training in multidisciplinary team settings
• Exposure to many disciplines
• Postdoctoral level health professionals and
  junior faculty from a variety of disciplines and
  clinical specialties (e.g., MD, DDS, PhD, PharmD,
  RN/PHD)
• Fall 2004 5 Program Sites Operational

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New NIH Policy Mentored Career Development K
Award Recipients

• To facilitate transition to independent NIH
  research support, mentored K award recipients can
  also hold concurrent research grants (e.g., RO1,
  PO1 or UO1 ) as the PI or Subproject Director in
  the last two years of their career award
• Permits candidates to continue to benefit from
  the mentoring and protected time offered by the K
  award
• Will adjust percent effort on K award (to no less
  than 50)
• Total level of research effort must not drop
  below 75
• See NIH Guide NOTICE NOT-OD-04-007
• Contact NIH Program Staff for specific policy
  guidelines

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NIH Extramural Loan Repayment Programs
(LRP)(www.lrp.nih.gov)

• Clinical Researchers LRP
• Clinical Researchers from Disadvantaged
  Backgrounds LRP
• Minority Health Disparities Research LRP
• Pediatric Research LRP
• Contraception and Infertility Research LRP

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NIH Extramural LRP

• Repayment of the educational loan debt of
  qualified health professionals
• Up to 35,000 per year of service
• Covers 39 Federal tax on loan repayment
• Must commit to a period of obligated service of
  no less than 20 hours a week for 2 years on the
  qualifying research project
• Renewal contracts considered on annual basis
• Next LRP Cycle opens on September 1, 2004 and
  closes on December 15, 2004

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Combined Fellowship in Reproductive Endocrinology
Infertility

• Four government institutions
• NICHD
• Walter Reed Army Medical Center
• National Naval Medical Center
• Uniformed Services University of the Health
  Sciences
• Candidates civilian and military residency
  graduates
• Three-year training program for Ob/Gyn fellows in
  REI who will serve as faculty in military,
  government and academic institutions
• Fellowship Director James Segars, M.D.

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NIH Research Funding Opportunities

• Program Announcement (PA)
• Request for Applications (RFA)
• Request for Proposals (RFP)
• Research Supplements Program Minority,
  Disability and Reentry

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Program Announcement (PA)

• Used by an institute to announce its interest in
  building or enhancing a research program in a
  particular area
• Highlights interest in a specific area of
  research
• Typically an ongoing solicitation, accepting
  grant applications for multiple receipt dates for
  up to 3 years
• Usually, no specific funds set aside
• May get special consideration if close to payline
  
• Reviewed by regular study sections

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Request for Applications (RFA)

• Solicitations for grant applications addressing
• a) a defined research topic of public health
  importance
• b) representing scientific opportunities
• c) research area in need of increased emphasis
• Funds set-aside for responsive applications that
  are meritorious
• Usually, a one-time solicitation
• Reviewed by a specially convened peer review
  panel

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NIH Research Supplements Program

• Research Supplements for Underrepresented
  Minorities (PA-01-079)
• Research Supplements for Individuals with
  Disabilities (PA-01-080)
• Supplements to Promote Reentry into Biomedical
  and Behavioral Research Careers
• (PA-01-081)

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NIH Research Supplements Program

• Basic program components
• Eligible candidates High School, Undergraduate,
  Graduate, Postdoc or Investigator level
• Underrepresented minorities are locally defined
• Administrative supplement to a funded grant
• Collaborate with a funded investigator on a
  research project
• Established PI with a major NIH grant is eligible
• Contact the PI
• Provides funding for salary, supplies and travel
• Relatively quick and non-bureaucratic
• Work with NIH staff

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Cooperative Reproductive Science Research Centers
at Minority Institutions

• Major sponsor NICHD
• Cosponsors ORWH, NCMHD
• Overarching Objectives
• To expand research capacity in reproductive
  science at minority institutions
• To create professional opportunities for minority
  investigators, especially those underrepresented
  within the scientific workforce
• To cultivate an academic and research milieu that
  will stimulate interest among students and
  fellows to pursue research careers in
  reproductive science
• To stimulate the development of a competitive
  research environment in reproductive science at
  minority institutions

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Cooperative Reproductive Science Research Centers
at Minority Institutions

• Morehouse School of Medicine Research projects
  at this Center integrate approaches at the
  molecular, cellular and organ levels to elucidate
  physiological mechanisms that govern sexual
  development, follicular maturation, luteolysis
  and spermatogenesis. PI David Mann, Ph.D.
  Collaborator Tony Plant, Ph.D., Univ. of Pitts.
• Meharry Medical College Research studies at this
  Center examine the effect of OCPs on leiomyoma
  growth, whether metformin vs. placebo combined
  with lifestyle interventions improve reproductive
  markers in adolescent and adult women with PCOS,
  and the impact of racial differences on sex
  steroids and their correlation with bone density
  and architecture. PI PonJola Coney, M.D.
  Collaborator Richard Legro, M.D., Penn. State
  Univ.
• Charles R. Drew University of Medicine and
  Science Therapeutic applications of androgens in
  normal women, women with hypopituitarism, and
  implications for conditions associated with loss
  of muscle mass and function as well as brain
  sexual differentiation provide several themes for
  research projects at this Center. PI Shalender
  Bhasin, M.D. Collaborator Gautam Chaudhuri,
  M.D., Ph.D., UCLA

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National Institutes of Health
Opportunities for Minority Investigators and
Minority Institutions at All Institutes, Centers
and Offices

• Including
• National Center on Minority Health and Health
  Disparities (NCMHD)
• National Center for Research Resources (NCRR)
• National Cancer Institute (NCI)
• National Institute of Allergy and Infectious
  Diseases (NIAID)
• National Institute of General Medical Sciences
  (NIGMS)
• National Institute of Child Health and Human
  Development (NICHD)

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For more information 

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• Please visit the following web sites 
• http//www.nih.gov
• http//www.nichd.nih.gov
• http//grants1.nih.gov/training/index.htm
• http//www.lrp.nih.gov