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Crystallographic RNA model building using backbone rotamers

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Crystallographic RNA model building using backbone rotamers. Kevin Keating. Pyle lab, Yale University. RNA Crystallography. RNA backbone rotamers ... – PowerPoint PPT presentation

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Title: Crystallographic RNA model building using backbone rotamers


1
Crystallographic RNA model building using
backbone rotamers
  • Kevin Keating
  • Pyle lab, Yale University

2
RNA Crystallography
3
RNA backbone rotamers
1a (helical)
4n
9a
5z
1
2o
4
RNA Crystallography
5
RNA Crystallography
6
Pseudotorsions
7
Rotamer Predictions
8
Rotamer Predictions
9
Rotamer Predictions
10
Rebuilt Test Cases
Sarcin/ricin domain (1Q9A)
Guanine riboswitch (2EES)
11
Rebuilt Test Cases
Guanine riboswitch (2EES) Suite 51
12
Rebuilt Test Cases
Guanine riboswitch (2EES) Suite 64
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