Bone Marrow Transplant Surgery in India - PowerPoint PPT Presentation

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Bone Marrow Transplant Surgery in India


Bone marrow transplant is a way of giving very high dose chemotherapy, sometimes with whole body radiotherapy. This treatment aims to try to cure some types of cancer, such as leukaemia, lymphoma and myeloma. The bone marrow is the spongy substance inside yourbones which makes all your blood cells. – PowerPoint PPT presentation

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Title: Bone Marrow Transplant Surgery in India

Bone Marrow TransplantThe Gift Of Life..
  • Deepam Meditours
  • (Medical Tourism Company)

What is Bone Marrow?
  • It is the soft tissue inside the bones that
    produces new blood cells. The new blood cells may
    grow into Red Blood Cells, White Blood Cells or

What is Bone Marrow Transplant?
  • It is the procedure in which unhealthy or
    diseased bone marrow is replaced with healthy
    bone marrow.
  • Blood Cells and healthy Marrow are needed to
  • Bone marrow is ideally extracted from the pelvis
    bone through a large needle that reaches the
    center of the bone.

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Who Needs Bone Marrow Transplant?
  • Leukemia (blood cancer disease) and also other
    type of cancer
  • Aplastic anaemia (bone marrow failure)
  • Other Genetic diseases (that involve the blood)
    or immune system diseases
  • Sickle Cell disease
  • Haemoglobinopathies

What are the types of Bone Marrow Transplants?
  • Autologous Bone Marrow Transplant
  • As the name suggests AUTO means SELF.
  • Lower risk of infection
  • Graft rejection is very rare as the donor and the
    recipient are the same person.
  • This process is common for diseases like lymphoma.

Allogeneic Bone Marrow Transplant
  • In this process the bone marrow is received from
    a donor.
  • HLA of the donor must be matched with HLA of the
  • Donor may be sister, brother, parents or other
  • There is a chance of rejection.

Umblical Cord / Cord Blood Transplant
  • The immature Marrow Cells recovered from the
    Umblical Cord of the new born baby after birth is
  • Cryopreserved Bone Marrow until they are needed
    for transplant.
  • This is highly beneficial as chances of mismatch
    are seldom.

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Factors to Choose Transplant Type
  • Type of disease being treated
  • The extent of bone marrow damage
  • Age and health of the patient

Donor stem cells can be collected in two ways
  • Bone marrow harvest
  • Minor surgery is done
  • The bone marrow is removed from the back of both
    hip bones.
  • The amount of marrow removed depends on the
    weight of the person who is receiving it.
  • Leukapheresis
  • Blood is removed from the donor through an IV
  • The part of white blood cells that contains stem
    cells is then separated in a machine and removed
    to be later given to the recipient.

Bone Marrow Transplant Procedure Includes
  • Extraction
  • Conditioning
  • Transplant
  • Engraftment and early recovery

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Risks of Bone Marrow Transplant
  • Chest pain
  • Drop in blood pressure
  • Fever, chills, flushing
  • Funny taste in the mouth
  • Headache
  • Hives
  • Nausea
  • Pain
  • Shortness of breath

Expected Result of BMT
  • The survival rate of Autologous transplant is 98
  • Allogeneic transplant survival rate is 73.2

Source Mayo Clinic
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