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Familial Cancer Risks

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... (standard errors) of breast cancer and ovarian cancer among relatives with BRCA1 ... Breast cancer. Ovarian cancer. BRCA1 or 2. BRCA1. BRCA2. BRCA1. BRCA2 ... – PowerPoint PPT presentation

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Title: Familial Cancer Risks


1
Ovarian cancer risk based on age
BRCA mutation (King, et. al.
Science. October 2003)
BRCA 1 BRCA 2 By age
40 3 out of 100 1 out of 50
(3) (2) By age 50 1 out
of 5 1 out of 50
(21) (2) By age 60 2 out of 5
3 out of 50 (40) (6) By age
70 1 out of 2 1 out of 8
(46) (12) By age 80 1
out of 2 1 out of 4 (54)
(23)
General Population (based on
SEER data) By age 40 ..1 out of 1,000
(0.12) By age 50 ..3 out of
1,000 (0.28) By age 60 ..6
out of 1,000 (0.58) By age 70
...1 out of 100 (0.98) By
age 80 ...1 out of 72
(1.39) Ever ... 1 out of 58
(1.72)
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