Objective for

1
Objective for
2
System of Quality of
3
Measure Life
4
Team Members

• Maja Middleton Team Leader
• Kayla Ericson Communicator
• Kristin Riching BSAC
• Katherine Davis - BWIG

5

• Client
• Dr. Erwin B. Montgomery M.D.
• Department of Neurology
• Advisor
• Prof. Justin Williams
• BME Department

6
Problem Statement

• Design a system or tool to measure the quality of
  life for a patient suffering from movement
  disorders.
• The system/device must provide evidence that the
  quality of life has improved post surgery so that
  insurance companies will continue to fund
  deep-brain stimulus rehabilitation.

7
Quality of Life

• Definition Quality of life is a measure of the
  means that people live within their own
  environments in ways that are best for them
• Applicable Definition The ultimate goal of deep
  brain stimulation surgery is to enable people to
  live quality lives -- lives that are both
  meaningful and enjoyed, but are also functional
  mentally, physically and socially.

8
Three Aspects of Quality of Life

• Mental Patients feelings and attitudes about
  themselves and their abilities as related to
  their disease and quality of life
• Cognitive assessment (PADLS or MSQOL54)
• Physical Patients ability to perform daily
  tasks
• Bluetooth accelerometer
• Social Patients daily interactions with
  society and personal relationships
• GPS
• All three aspects will be measured pre- and
  post-surgery

9
Product Design Specifications
10
Background Material and Research

• Movement Disorder Symptoms
• Rigidity
• Postural Instability
• Tremor
• Bradykinesia / akinesia
• Slowness
• Absence of movement
• Dyskinesia
• Abnormal, involuntary movement
• Side effect of drug therapy

11
Previous Methods

• No previous devices for objective measure of
  movement disorders found besides written
  questionnaires and doctor judgment.
• Doctor observation is becoming less accepted as
  insurance companies lean toward evidence based
  medicine

12
Background Material and Research

• Insurance companies only pay for necessary
  rehabilitation treatments that bring the patient
  to a normal functioning level for their
  environment
• They continue to fund treatments so long as
  progress continues
• All progress is marked on a scale that relates to
  daily functions of life
• Reaching, lifting, standing, walking, dressing,
  etc

13
Deep Brain Stimulation

• For neurologically based movement disorders
• Two electrodes implanted in the brain are fed to
  a pulse generator implanted in the chest
• The generator delivers high-frequency
  electrical stimulation that shuts down
  nerve cells to allow cells to regain
  self-control

Figure 1 http//www.clevelandclinic.org/neuroscie
nce/techniques/dbs.htm
14
Physical Design Specifications

• Accelerometers
• 5 subunits
• One for each wrist (2 total)
• One for each ankle (2 total)
• One on the trunk as a reference
• Bluetooth enabled
• Allows for wireless messaging of data to
• the central PDA

35 mm
Depth 5mm
35 mm
Figure 2 Top picture - front view bottom
picture back view http//www.gvu.gatech.edu/ccg/
resources/btacc/index.html
15
Physical Technical Aspects

• All accelerometers need to communicate together
  done via the PDA and Bluetooth technology
• Each signal must be recognized individually by
  the PDA (X, Y, Z data in ASCII format number
  for a character)
• Will sample at 20 Hz (Nyquis Theorem)
• Battery life (Lithium ion) is about 60 hours (840
  mAh 3.7V)
• Has A-D conversion

16
Central Integration Unit

• Hewlett Packard - Personal Desktop
  Assistant (PDA)
• Bluetooth enabled PDA
• CompactFlash slot
• Expansion slot in PDA for memory capabilities
• USB port for easy PC interfacing

HP iPAQ2215
Figure 3 http//www.circuitcity.com/detail.jsp?c
1bgucqp0bookmarkbookmark_0oid74016catoi
d-8028m0
17
Central Unit Technical Aspects

• PDA
• 64 MB internal RAM
• Up to 512 MB of add-on memory
• 900 mAh lithium rechargeable battery
• Software must be programmed for PDA to record and
  store GPS data (every half hour)
• Software must also be programmed to receive,
  store, and manipulate accelerometer data
• All programming will be done using the software
  development kit (SDK) from Microsoft

18
Social Design Specifications

• Laipac Global Positioning System (GPS)
• Tracking GPS compact flash card (to log distance
  and location)
• Low power consumption
• Windows compatible

Figure 4 http//www.laipac.com/gps_tf30cf_eng.htm
19
Social Technical Aspects

• GPS
• Record readings every half hour
• Accurate to 25 m
• 3.3 V
• .2 W power consumption
• PDA driver is downloadable from the website

20
Thank you!

• We just want to extend our thanks to
• Dr. Montgomery
• Prof. Justin Williams
• Dr. Jim Abbs
• Daryn Belden
• Gary Diny, PT

21
Future Work

• The plan for the device is thoroughly mapped out.
  The next steps include
• Purchasing the PDA and CompactFlash card
• Writing the software with the SDK for the GPS
• Purchasing the pieces for the accelerometer
• Purchasing the circuit board and assembling the
  system
• Design and build casing for the accelerometers
• Write software using the SDK for the
  accelerometer
• Test the integrated system

22
Overall schematic
Reference Accelerometer
Integrated PDA and GPS
Upload data to PC
Accelerometer
Figure 5 www.circuitcity.com
23
References

• Davis, William R. Personal Interview. 14 Feb.
  2004.
• Department of Neurology. (2001). What are
  Movement Disorders and How are they Treated?
  Retrieved March 8, 2004, from Baylor College of
  Medicine Web site http//www.bcm.tmc.edu/neurol/s
  truct/park/park6.html
• Diny, Gary. Personal Interview. 27 Feb. 2004.
• Hobson, J.P., et al., eds. The Parkinsons
  Disease Activities of Daily Living Scale a new
  simple and brief subjective measure of disability
  in Parkinsons disease. Clinical Rehabilitation
  151 (2001) 241-246.
• Meyers, Allan R., et al., eds. Health-Related
  Quality of Life in Neurology. Neurology and
  Public Health 571 (2000) 1224-1227.
• Montgomery, Erwin B. Personal Interview. 27 Jan.
  2004.
• Deep Brain Stimulation surgery. Retrieved April
  25, 2004. http//www.clevelandclinic.org/neuroscie
  nce/techniques/dbs.htm
• Deep Brain Stimulation Surgery. Retrieved April
  25, 2004. www.wemove.org