Effects of composite transcription factor modulation of human fibroblasts: Conclusions

1
Effects of composite transcription factor
modulation of human fibroblasts Conclusions

• Induced pluripotent stem cells can be generated
  from human fibroblasts by retroviral transduction
  of transcription factors
• Use of vectors that may integrate into genome,
  introducing mutations, precludes any clinical
  application at present

Takahashi K et al. Cell. 2007.Yu J et al.
Science. 2007.