A Lifetime of Biomedical Computing: A Conversation with Robert Ledley

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A Lifetime of Biomedical Computing A
Conversation with Robert Ledley
The Office of NIH History Presents

• Lister Hill Auditorium
• February 21, 2008

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SEAC (Standards Eastern Automatic Computer)

• Operational in 1950
• Early stored-program electronic computer
• Initially not transistorized logic in 750 to
  1500 vacuum tubes
• 512 45-bit words of memory
• Paper tape
• Cycle speed 1 MHz

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SEAC (Standards Eastern Automatic Computer)
SEAC operator Terry Ledley in 1952
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DYSEAC trailer circa 1955
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George Gamow 1904-1968
Source James Watson, Girls, Genes, and Gamow,
2003.
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Ledleys RNA encoding matrix. Source Robert S.
Ledley Digital Computational Methods in Symbolic
Logic, with Examples in Biochemistry,
Proceedings of the National Academy of Sciences
41 (July 1955), 505 (fig. 2).)
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FIDAC
Film Input to Digital Automatic Computer 1964
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Ledley operating IBM 360/44 (circa 1966)
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Margaret Oakley Dayhoff (1925-1983)
Source www.dayhoff.cc
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Margaret Dayhoff circa 1980
Source NBRF
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Ledley with ACTA at the Museum of American
History (late 1970s)
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ACTA at Georgetown University circa 1975
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