ROLES OF IF1 AND IF3 IN RIBOSOME DISSOCIATION

1
ROLES OF IF-1 AND IF-3 IN RIBOSOME
DISSOCIATION IF-1 PROMOTES DISSOCIATION OF THE
RIBOSOMAL SUBUNITS IF-3 PREVENTS REASSOCIATION OF
30S SUBUNIT WITH 50S SUBUNIT
WEAVER FIG. 17.9
2
(No Transcript)
3
STRUCTURE OF THE COLICIN FRAGMENT (3 49
NUCLEOTIDES) OF E. coli 16S RNA AND THE
TRANSLATIONAL INITIATION REGION OF PHAGE R17 A
PROTEIN CISTRON
WEAVER FIG. 17.13
4
(No Transcript)
5
IF-1 AND IF-3 TOGETHER STIMULATE THE BINDING OF
IF-2 TO THE 30S RIBOSOMAL SUBUNIT
WEAVER FIG. 17.16
6
(No Transcript)
7
PROTEIN SYNTHESIS IN PROKARYOTES PROOFREADING
AND ELONGAGATION
8
(No Transcript)
9
(No Transcript)
10
(No Transcript)
11
(No Transcript)
12
(No Transcript)
13
(No Transcript)
14
SOME OF THE ANTIBIOTICS THAT INHIBIT
TRANSLATION THROUGH THEIR ACTION ON RIBOSOMES
CHLORAMPHENICOL Inhibits peptidyl trans-
ferase on prokaryotic 50S subunit SREPTOMYCIN
Causes mRNA misreading and inhibits
initiation in prokaryotes TETRACYCLINE Inhibits
binding of amino- acyl-tRNAs to prokaryotic
30S subunit ERYTHROMYCIN Inhibits translocation
on prokaryotic 50S subunit CYCLOHEXIMIDE
Inhibits peptidyl transferase on eukaryotic
large subunit
WEAVER FIG 18.10
15
(No Transcript)
16
THE MECHANISM OF INHIBITION OF TRANSLATION BY
PUROMYCIN
WEAVER FIG. 18.11
17
(No Transcript)
18
(No Transcript)
19
(No Transcript)
20
(No Transcript)
21
SPECIFICITY OF RELEASE FACTORS RF-1 AND RF-2
WEAVER FIG. 18.34
22
MECHANISM OF SUPPRESSION
WEAVER FIG. 18.32
23
E. coli AMBER SUPPRESSOR tRNATyr DIFFERS FROM
WILD-TYPE tRNATyr BY A SINGLE NUCLEOTIDE IN THE
ANTICODON
WEAVER FIG. 18.31