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Radiological Terrorism

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Purgatives, laxatives, and enemas can be administered to reduce colon exposure ... Debridement and cleansing for skin wounds. Dirty Bomb: Summary ... – PowerPoint PPT presentation

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Title: Radiological Terrorism


1
Radiological Terrorism
  • The Dirty Bomb

2
Dirty Bomb Overview
  • A radiation dispersion device, or RDD
  • Conventional explosive device with radioactive
    material added
  • Radioactive material spreads to surrounding area
    by physical dispersion and airborne diffusion

3
Dirty Bomb Overview
4
Dirty Bomb Overview
  • Extent of contamination
  • Size and sophistication of the bomb
  • Type of radioactive material
  • Weather conditions
  • Extent of human exposure
  • Speed of evacuation from contaminated area
  • Example
  • Bomb with a single cobalt-60 rod
  • Acute dose of a few tenths of a rem to people
    within a half-mile radius

5
Dirty Bomb The Threat
  • Threat of fear and disruption
  • Panic over radiation exposure
  • Produce additional casualties
  • Disrupt rescue and evacuation efforts
  • Disruption arises from area remaining off-limits
    and unusable during clean-up work

Hazardous Materials Response Austin, TX Fire
Department Image
6
Dirty Bomb Materials
  • Most likely to be used cobalt-60, strontium-90,
    cesium-137, and americium-241
  • Less likely phosphorus-32 and radium-226
  • Obtained from military, medical, industrial,
    academic or research sources
  • Examples
  • Cobalt-60 food and mail irradiation
  • Americium-241 smoke detectors and oil
    exploration
  • (See Radiation Primer for more on these
    isotopes)

7
Dirty Bomb Health Risks
  • Radionuclides cross capillary membranes through
    passive and active diffusion
  • Rate of distribution
  • Organ metabolism
  • Ease of chemical transport
  • Affinity of radionuclide for chemicals in organs
  • Liver, kidney, adipose tissue, and bone
  • Greatest capacity for binding radionuclides
  • Higher protein and lipid makeup

8
Dirty Bomb Health Risks
  • Major health risks
  • Acute trauma from the explosion itself
  • Cancer
  • Specific target organ damage
  • Heavy metal poisoning

9
Dirty Bomb Health Risks
  • Cancer risk is not known
  • Tumor induction statistics extrapolated from data
    on known exposures at doses gt100 rem
  • Extrapolated data may be inaccurate for exposures
    lt 100 rem

10
Dirty Bomb Health Risks
  • Linear, no threshold model
  • Endorsed by the EPA and American Federation of
    Scientists
  • Non-linear, threshold model
  • Endorsed by the Health Physics Society and
    International Council on Radiation Protection

11
Dirty Bomb Health Risks
  • Linear, no threshold model
  • Biological damage follows a linear progression
    with exposure levels
  • The higher the dose, the greater the damage
  • Used to extrapolate data on exposures lt 100 rem
  • Presents a worst-case scenario

12
Dirty Bomb Health Risks
  • Non-linear, threshold model
  • Biological damage does not follow a linear
    progression with exposure levels
  • Data supports a threshold in excess of 10 rem
  • Delivered at high dose rates
  • 0.8 increase in lifetime risk for cancer
  • Allows for cellular repair at lower doses
  • 10 rem at low dose rates may not increase the
    risk

13
Dirty Bomb Health Risks
  • Acute Radiation Syndrome unlikely
  • Also unlikely
  • Other known sequelae of radiation exposure
  • Cataract formation
  • Decreased fertility
  • Fetal teratogenesis
  • Chronic Radiation Syndrome
  • Requires at least 100 rem to bone marrow over a
    several year time span

14
Dirty Bomb Decontamination
  • Primary contaminants alpha and gamma emitters
  • Shoe and clothing removal will reduce
    contamination by 90
  • Other external contaminants are particulates that
    can be washed off the skin and hair
  • Internal contaminants pose no secondary threat to
    healthcare workers

15
Dirty Bomb Signs and Symptoms
  • The primary injuries, and their associated signs
    and symptoms, will be related to blast trauma
  • Signs and symptoms of Acute or Chronic Radiation
    Syndromes will not be seen
  • (See Nuclear Reaction for more on these
    syndromes)

16
Dirty Bomb Treatment
  • Inhalation exposures
  • Particles lt5 microns move into the alveoli
  • Soluble particles absorbed into blood stream and
    lymphatic system
  • Mucociliary apparatus will clear larger particles
  • Inflammatory response with subsequent fibrosis
    and scarring
  • Clearance of these insoluble particles
  • Sputum induction and pulmonary toilet

17
Dirty Bomb Treatment
  • Ingestions
  • Absorption depends on chemical state of the
    contaminant
  • Cesium salts are quickly absorbed
  • Cobalt, radium, and strontium are not absorbed
  • Lower GI tract becomes target organ for residual
    radionuclides

18
Dirty Bomb Treatment
  • Ingestions
  • Gastric lavage and emetics help clear stomach
  • Purgatives, laxatives, and enemas can be
    administered to reduce colon exposure
  • Inhaled particles cleared by the mucociliary
    apparatus end up in the GI tract
  • Consider ion exchange resins to reduce GI uptake
    of these and other ingested radionuclides

19
Dirty Bomb Treatment
  • Skin
  • Impermeable to most radionuclides
  • Wounds and burns allow radioactive particles to
    by-pass the epithelium
  • Meticulously clean and debride all wounds and
    burns

20
Dirty Bomb Treatment
  • Heavy metal poisoning
  • Consider chelation therapy where appropriate
  • Calcium edetate (EDTA)
  • Used primarily to treat lead poisoning
  • Also consider dimercaprol and penicillamine
  • DTPA more effective in removing many of the
    heavy-metal, multivalent radionuclides

21
Dirty Bomb Treatment
  • Isotope specific treatments
  • Americium-241
  • Use DTPA or EDTA chelation in the first 24 to 48
    hours following pulmonary exposure
  • Cesium-137
  • Early use of lavage and purgatives
  • Prussian blue and ion exchange resins are useful

22
Dirty Bomb Treatment
  • Isotope specific treatments
  • Cobalt-60
  • Gastric lavage and purgatives for ingestions
  • Penicillamine chelation in severe cases
  • Phosphorus-32
  • Lavage, aluminum hydroxide, and oral phosphates.

23
Dirty Bomb Treatment
  • Isotope specific treatments
  • Radium-226
  • Immediately lavage after ingestion
  • Fecal elimination may be increased by ammonium
    chloride

24
Dirty Bomb Treatment
  • Isotope specific treatments
  • Strontium-90
  • Oral administration of aluminum phosphate
    immediately after ingestion
  • Administration of stable strontium
  • Calcium and acidification of the urine with
    ammonium chloride will increase excretion

25
Dirty Bomb Summary
  • Known as a radiation dispersal device (RDD)
  • Conventional explosive device with radiological
    material added
  • Main threat is one of fear and disruption
  • Most likely radioisotopes to be used cobalt-60,
    strontium-90, cesium-137, and americium-241

26
Dirty Bomb Summary
  • Major health risks include
  • Acute blast trauma
  • Cancer
  • Specific target organ damage
  • Heavy metal poisoning
  • A non-linear, threshold model of exposure is
    favored by health physicists

27
Dirty Bomb Summary
  • Primary injuries will be related to blast trauma
  • Signs and symptoms of Acute or Chronic Radiation
    Syndromes will not be seen
  • Treatment rapid elimination of the radionuclide
    from the body
  • Pulmonary toilet for inhalation exposures
  • Gastric lavage and purgatives for ingestions
  • Debridement and cleansing for skin wounds

28
Dirty Bomb Summary
  • Chelation therapy for cases of potential heavy
    metal poisoning
  • Specific treatment regimens advised for each
    isotope with potential for use in a RDD
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