DIARRHEAL DISEASES - PowerPoint PPT Presentation

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DIARRHEAL DISEASES

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DIARRHEAL DISEASES Defence mechanisms Gastric acidity GI peristalsis Normal flora Immune defences Pathogenesis of diarrhea Villous damage Enterotoxin Cytotoxin ... – PowerPoint PPT presentation

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Title: DIARRHEAL DISEASES


1
DIARRHEAL DISEASES
2
Defence mechanisms
  • Gastric acidity
  • GI peristalsis
  • Normal flora
  • Immune defences

3
Pathogenesis of diarrhea
  • Villous damage
  • Enterotoxin
  • Cytotoxin
  • invasion

4
Causes of gastroenteritis
  • Viruses
  • Bacteria
  • parasites

5
Rotvirus gastroenteritis
  • Infants children
  • Destuction of brush border
  • Usualy mild to moderate diarrhea
  • If severe dehydration,shock
  • Diagnosis exclude other causes
  • Treatment fluids PO/IV

6
Salmonella gastoenteritis
  • Cause salmonella enteritides
  • Source GIT of animals
  • Presentation abdominal pain, nausea, vomiting
    ,diarrhea /- fever
  • Diagnosis stool microscopy culture
  • Treatment fluids PO/IV
  • Antibiotics only for severe cases or
    impaired immunity


7
Shigellosis
  • Transmission contaminated food or drink
  • Causes invasive colitis
  • Presentation abdominal pain,diarrhea, fever
    dysentry
  • Diagnosis stool microscopy culture
  • Treatment fluids antibiotics

8
Campylobacter gastroenteritis
  • Source GIT of animals
  • Causes invasive enterocolitis
  • Transmission contaminated food or drink
  • Presentationfever, malaise, abd.pain
    diarrhea blood
  • Diagnosis stool microscopy culture
  • Treatment fluids antibiotics

9
E.Coli gastroenteritis
  • Normal flora of GIT
  • Pathogenic mechanisms gt enterotoxigenic gt
    enteropathogenic gt enteroinvasive
  • Diagnosis by exclusion
  • Treatment fluids

10
Cholera
  • Transmissioncontaminated food or drink
  • Pathogenesis enterotoxin
  • Presentation asymptomatic mild if severe
    dehydration shock
  • Diagnosis stool culture
  • Treatment fluids antibiotic

11
Amebiasis
  • Transmission by cysts
  • Causes invasive colitis
  • Presentation asymptomatic acute
    dysentry chronic amebiasis
  • Complications liver abscess
  • Diagnosis stool microscopy , serology
  • Treatment metronidazole

12
Giardiasis
  • Transmission
  • Colonise upper small intestine
  • Presentation asymptomatic mild to
    moderate abd. pain , flatulence
  • May become chronic
  • Diagnosis stool microscopy
  • Treatment metronidazole

13
Food poisoning
  1. Vomiting within 6 hrs of eating
  2. Abd pain , diarrhea after 8 16 hrs
  3. Abd. Pain , diarrhea after 16 48 hrs
  4. Abd. Pain, diarrhea , fever 16- 48 hrs
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