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Supplementary Figure 1

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30000 Luciferase activity 29000 28000 27000 26000 25000 24000 23000 Rocovitine (mM) 0.16 0.31 0.63 6.25 12.5 100 200 1.5 25 50 0 3 Supplementary Figure 1 0 20 40 60 ... – PowerPoint PPT presentation

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Title: Supplementary Figure 1


1
Supplementary Figure 1
2
A)
Clone A
Clone B
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0
0
0
0
0
0
0
0
Vector
Vector
WT
S393A
WT
S393A
Supplementary Figure 2
3
B)
32P E1
C)
aa 388-402
aa 516-530
32P E1
CDK1 /CycB
Supplementary Figure 3
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Supplementary Figure 4
5
E1 WT
Con
B)
-
ROSC(10mM)

-
NUC
CYT
Supplementary Figure 5
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A)
B)
EBNA1
EBNA1 S393
WT
S393A
naked oriP
oriP in cell
ROCO (20uM)
-
-


-

-

.1
.5 ng
ROSC (10mM)
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4
4
11
Day
oriP episome
Loading
Day 21 in Puro
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114
73
64
100
428
Day
D)
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12
Cell No. (x109)
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4
2
Supplementary Figure 6
0
0
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21
Days in culture in Puro
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