CLUB DRUGS

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CLUB DRUGS

• DANCE TILL YOU DROP

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MAJOR CLUB DRUGS

• MDMA/ECSTASY
• GHB/GBL
• KETAMINE
• NITROUS OXIDE
• POPPERS
• LSD

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MISCELLANEOUS DRUGS

• 2C-B
• GBL GAMMA BUTYL LACTONE
• DEXTROMETHORPHAN
• HERBAL ECSTASY
• MUSHROOMS

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ESCTASY

• MDMA
• METHYLENEDIOXYMETHAMPHETAMINE
• ADAM
• X-TC
• CLARITY
• ESSENCE
• STACY
• LOVERS SPEED
• EVE

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DOSAGES

• THRESHOLD 30 MG
• AVERAGE 75-125 MG
• LETHAL DOSE 106 - 6000MG

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MDMA ACTIONS

• DURATION
• PRIMARY EFFECTS 3-4 HRS
• CRASH 2-6 HRS
• HANGOVER
• (MAY LAST UP TO 5 DAYS)
• POST MDMA DEPRESSION

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MECHANISM OF ACTION

• DECREASES DOPAMINE RELEASE
• INHIBITS REUPTAKE OF SEROTONIN
• RELEASES SEROTONIN
• RESEMBLES HYBRID AMPHETAMINE
• MESCALINE

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COMMONCONTAMINANTS

• CHALK
• LSD
• AMPHETAMINES
• HEROIN
• CAFEINE
• KETAMINE
• EPHEDRINE

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ECSTASYBEHAVIORAL EFFECTS

• INCREASED ENERGY
• EMPATHY TOWARD OTHERS
• INCREASED AFFECTION
• EMOTIONAL OPENNESS
• PROFOUND POSITIVE FEELINGS
• EUPHORIA
• DECREASED INHIBITIONS
• DECREASED ANXIETY
• EXTREME RELAXATION

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MDMA ACUTE EFFECTS

• TEETH CLENCHING
• NAUSEA
• HALLUCINATION
• CHILLS
• SWEATING
• TREMORS
• BLURRED VISION
• MUSCLE CRAMPING

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ACUTE SIDE EFFECTS

• HYPERTHERMIA
• INCREASED BODY TEMPERATURE
• DEHYDRATION
• CARDIOVASCULAR STIMULATION
• METABOLIC ACIDOSIS
• RHAMDOMYOLOSIS
• MUSCLE BREAKDOWN

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ACUTE TOXICITY

• HYPERTHERMIA
• CONVULSIONS
• DISSEMINATED INTRAVASCULAR COAGULATION
• ACUTE RENAL FAILURE
• CARDIAC ARRYTHMIAS
• HEPATITIS

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MDMA OVERDOSE

• HIGH BLOOD PRESSURE
• FAINTNESS
• PANIC ATTACKS
• LOSS OF CONSCIOUSNESS
• SEIZURES
• HEART FAILURE
• HEAT STROKE

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MDMA AFTER EFFECTS

• ANXIETY
• PARANOIA
• DEPRESSION

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MDMA PERMANENT DAMAGE

• DEPRESSION
• ANXIETY
• MEMORY LOSS
• CHANGES IN SLEEP PATTERNS
• LEARNING IMPAIRMENTS
• EMOTIONAL PROBLEMS

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MDMA TOXICITY

• SIMILAR TO HEAT STROKE
• URINARY pH LESS THAN 5.6 IN METABOLIC ACIDOSIS
• CAUSES MYOGLUBIN CASTS
• HYPERKALEMIA RELATED TO CARDIAC ARRYTHMIA
• WATER INTOXICATION

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NEUROTOXICITY

• NEURONAL DAMAGE
• DECREASE IN DOPAMINE
• LOSS OF SEROTONIN NERVE TERMINALS
• PARKINSONISM
• APPETITE SUPPRESSION

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PROTECTIVE MEASURES?

• VIAGRA FOR SEXUAL PROBLEMS
• SSRIs e.g. PROZAC
• DRUGS THAT BLOCK DA RELEASE
• ANTIOXIDANTS

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GHB

• GAMMA HYDROXYBUTYRATE
• LIQUID X, GREVIOUS BODILY HARM
• CNS DEPRESSANT
• ALSO USED BY BODY BUILDERS
• SALTY TASTING LIQUID
• ONSET OF ACTION 10-20 MIN
• EFFECTS LAST UP TO 4 HOURS
• CLEARED QUICKLY

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GHB USES

• INTOXICATING PROPERTIES
• SEDATIVE ACTIONS
• EUPHORIC EFFECTS
• RELIEVE ANXIETY
• PRODUCE RELAXATION
• GH RELEASING PROPERTIES

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GHB OVERDOSE

• DROWSINESS
• NAUSEA/VOMITING
• HEADACHE
• LOSS OF CONSCIOUSNESS
• LOSS OF REFLEXES
• IMPAIRED BREATHING
• COMA/DEATH

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GHB DANGERS

• DROWSINESS
• DIZZINESS
• NAUSEA
• UNCONSCIOUSNESS
• SEIZURES
• SEVERE RESPIRATORY DEPRESSION
• COMA
• DEATH

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GHB WITHDRAWAL

• ANXIETY
• RESTLESSNESS
• INSOMNIA
• RAPID HEART BEAT
• NAUSEA

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GHB DEATH LIST
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KETAMINE

• SEDATIVE-HYPNOTIC
• SPECIAL k k
• GENERAL ANESTHETIC
• HALLUCINOGEN
• ANALGESIC
• RAPID ONSET
• LASTS ONE HOUR

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KETAMINE EFFECTS

• IMPAIRED COORDINATION
• IMPAIRED JUDGEMENT
• PERISTENT MEMORY PROBLEMS
• PSYCHOTIC SYMPTOMS
• DREAMLIKE STATES
• HALLUCINATIONS
• NEAR DEATH EXPERIENCE (K-HOLE)
• SENSORY IMPAIRMENT

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NITROUS OXIDE

• LAUGHING GAS
• DISSOCIATIVE ANESTHETIC
• AVAILABLE IN WHIPPITS
• INHALED FROM TANK OR BALLOONS
• EFFECTS IMMEDIATE SHORT-LIVED

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NITROUS EFFECTS

• EUPHORIA
• ANALGESIA
• LOSS OF CONSCIOUSNESS

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ADVERSE EFFECTS

• TEMPORARY LOSS OF MOTOR CONTROL
• SENSATIONS PERCEPTIONS DISCONNECTED
• DREAMY MENTAL STATE
• MILD AUDIO VISUAL HALLUCINATIONS

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DANGERS

• COLD GAS BURNS LIPS, THROAT, LUNGS
• HYPOXIA
• LONG-LASTING NUMBNESS IN EXTREMITIES

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POPPERS

• AMYL NITRATE/BUTYL NITRATE
• RELAX SMOOTH MUSCLE
• PRODUCE FEELING OF RUSH
• FLUSHING
• DIZZINESS
• HEADACHE
• PROGRESSIVE LOSS OF CONSCIOUSNESS

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LSD

• POTENT HALLUCINOGEN
• ERGOT FUNGUS
• 30 ?g DOSE
• ONSET WITHIN 30-90 MIN
• HIGH LASTS 6-12 HOURS

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LSD EFFECTS

• DILATED PUPILS
• HIGHER BODY TEMPERATURE
• INCREASED HEART RATE
• INCREASED BLOOD PRESSURE
• SWEATING
• DRY MOUTH
• TREMORS
• NUMBNESS/WEKNESS

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LSD ACTIONS

• DILATED PUPILS
• INCREASED BODY TEMPERATURE
• INCREASED HEART RATE
• INCREASED BLOOD PRESSURE
• LOSS OF APPETITE
• INCREASED SWEATING
• DRY MOUTH
• TREMORS

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BAD TRIP

• TERRIFYING THOUGHTS
• SEVERE AGITATION
• FEAR OF LOSING CONTROL
• FEAR OF INSANITY DEATH
• SEVERE ANXIETY
• SUICIDAL THOUGHTS
• PRECIPITATE PSYCHOSIS
• ACCIDENTAL DEATH

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LSD PSYCHOSIS

• AFFECT PERCEPTION OF REALITY
• INABILITY TO THINK RATIONALLY
• DRAMATIC MOOD SWINGS
• VIVID VISUAL DISTURBANCES
• HALLUCINATIONS

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HALLUCINOGEN PERSISTINGPERCEPTION DISORDER
(HPPD)

• EPISODIC VISUAL DISTURBANCES
• FLASHBACKS
• FALSE FLEETING PERCEPTIONS
• FLASHES OF COLOR
• GEOMETRIC PSEUDOHALLUCINATIONS
• POSITIVE AFTERIMAGES
• PERMANENT ALTERATION IN VISUAL SYSTEM

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PCP

• DEVELOPED IN 1950
• WAS USED AS IV ANESTHETIC
• DISSOCIATIVE OUT OF BODY
• PRODUCES DELIRIUM
• EXTREME AGITATION
• RAPID ONSET
• LASTS FOR SEVERAL HOURS

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PCP ACTIONS

• DISRUPTS NMDA RECEPTORS
• AFFECT GLUTAMATE ACTIVITY
• GLUTAMATE ROLE IN PAIN, COGNITION, LEARNING
  MEMORY
• ALSO AFFECTS DA CAUSING EUPHORIA OR RUSH

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PCP EFFECTS

• SHALLOW RAPID BREATHING
• INCREASED BLOOD PRESSURE
• INCREASED HEART RATE
• ELEVATED TEMPERATURE
• NAUSEA
• BLURRED VISION
• DECREASED PAIN AWARENESS

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PCP EPISODE

• DETACHEMENT FROM REALITY
• DISTORTION OF TIME/SPACE
• ALTERED BODY IMAGE
• FEELING INVULNERABLE
• EXAGGERATED STRENGTH
• SEVERE DISTORIENTATION
• SUICIDAL BEHAVIOR

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DEXTROMETHORPHAN

• OTC COUGH MEDICINE
• NMDA ANTAGONIST
• DISSOCIATIVE EFFECTS

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ROHYPNOL

• FLUNITRAZEPAM
• ROOFIES
• ILLEGAL IN US
• TASTELESS/ODORLESS
• 1 MG DOSE LASTS 8-12 HOURS

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ROHYPNOL ACTIONS

• SEDATIVE EFFECTS 10X THAN VALIUM
• EFFECTS APPEAR 15-20 MIN
• LAST 4-6 HOURS
• RESIDUAL EFFECTS UP TO 12 HOURS

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ROHYPNOL USES

• BOOST HIGH FROM ALCOHOL
• BOOST HIGH FROM HEROIN
• MODULATE COCAINE EFFECTS
• RAVE DRUG
• DATE RAPE DRUG

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ROHYPNOL ADVERSEEFFECTS

• LOSS OF MOTOR CONTROL
• LACK OF COORDINATION
• SLURRED SPEECH
• CONFUSION
• GI DISTRESS
• RESPIRATORY DEPRESSION
• IMPAIRED COGNITION
• AMNESIA

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METHAMPHETAMINE EFFECTS

• MEMORY LOSS
• VIOLENCE
• PSYCHOTIC BEHAVIOR
• CARDIAC ARRYTHMIAS
• NEUROLOGICAL DAMAGE

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METH TOXICITY

• REDUCTION IN DA TRANSPORTERS
• MASSIVE RELEASE OF DA NE

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