Basic

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CD4
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CD4
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CD8
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3-5 days 3 times/day gt10000 folds
Lymph node
Naïve T cells can live for many years
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Immunity to extracellular bacteria
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Immunity to intracellular bacteria
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Bacteria in the cytosol activate CTLs against
bacteria-infected cells
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Immunity to viruses
The defense mechanisms used to clear a primary
infection are identified by the red shading of
the boxes where these are known. Yellow shading
indicates a role in protective immunity. Paler
shades indicate less well established mechanisms.