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Reporting on Scientific Journal Articles

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Reporting on Scientific Journal Articles Jeremy Moore, M.A. Senior Manager, Science Communications American Association for Cancer Research jeremy.moore_at_aacr.org – PowerPoint PPT presentation

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Title: Reporting on Scientific Journal Articles


1
Reporting on Scientific Journal Articles
  • Jeremy Moore, M.A.
  • Senior Manager, Science Communications
  • American Association for Cancer Research
  • jeremy.moore_at_aacr.org

2
Why is Cancer Newsworthy?
3
Why is Cancer Newsworthy?
  • Number 1 cause of death, surpassing heart disease
    in 2010

4
Why is Cancer Newsworthy?
  • Number 1 cause of death, surpassing heart disease
    in 2010
  • In the United States, it affects one in three
    women and one in two men

5
Why is Cancer Newsworthy?
  • Number 1 cause of death, surpassing heart disease
    in 2010
  • In the United States, it affects one in three
    women and one in two men
  • Consequences both biological and psychological

6
Why is Cancer Newsworthy?
  • Money

7
Why is Cancer Newsworthy?
  • Money
  • Government Money
  • NCI Budget, 2009 4.96 billion
  • NCI Budget, 2010 5.1 billion

8
Why is Cancer Newsworthy?
  • Money
  • Government Money
  • NCI Budget, 2009 4.96 billion
  • NCI Budget, 2010 5.1 billion
  • Budget Request for 2011
  • 5.26 Billion

9
Why is Cancer Newsworthy?
  • Money
  • Private Money

10
Why is Cancer Newsworthy?
  • Money
  • Private Money
  • Corporate and Philanthropic

11
Scientific Inquiry
  • In fact I have not failed 1,000 times.
  • I have successfully discovered 1,000 ways not to
    make a light bulb.
  • --Thomas Edison

12
Scientific Inquiry
  • Cancer

13
Scientific Inquiry
  • Cancer
  • Out of control cell growth

14
Scientific Inquiry
  • Cancer
  • Out of control cell growth
  • More than 200 diseases

15
Cancer
  • CURE?

16
Cancer
  • CURE
  • vs.
  • CONTROL

17
Cancer The Scientific Questions
  • Diagnosis

18
Diagnosis
  • Bladder Cancer
  • Pancreatic Cancer
  • Ovarian Cancer
  • Breast Cancer
  • Colon Cancer
  • Skin Cancer

19
Cancer The Scientific Questions
  • Diagnosis
  • Screening

20
Screening
  • Questions surrounding PSA, Mammography,
    Colonoscopy

21
Sensitivity vs. Specificity
  • Sensitivity
  • Specificity
  • Correctly Identifying Who Is Sick
  • Correctly Identifying Who Is Not Sick

22
MicroRNA
  • The discovery of MicroRNA can be equated with
    the idea that weve known for years that cars
    existed and only recently discovered they have a
    transmission. Its that fundamental.
  • Philip Sharp, Ph.D., Nobel Laureate from M.I.T.

23
MicroRNA News from Annual Meeting 2010
  • miR-21 and miR-106a are associated with an
    overall poor prognosis and that overexpressions
    of miR-181b and miR-203 are associated with poor
    outcomes in blacks for colorectal cancer
  • MicroRNA-31 (miR-31) repressed specific tumor
    suppressors and, therefore, may be a novel
    pharmacologic target for lung cancer therapy and
    chemoprevention.

24
MicroRNA News from Annual Meeting 2010
  • High levels of miR-21 were significantly
    correlated with poor response to Herceptin.

25
DNA Methylation Levels
26
Cancer The Scientific Questions
  • Diagnosis
  • Screening
  • Personalized Medicine

27
Personalized Medicine
28
Cancer The Scientific Questions
  • Diagnosis
  • Screening
  • Personalized Medicine
  • Prevention

29
Prevention
  • At least half of all cancer deaths are
    preventable by what we already know about healthy
    eating, exercise, maintaining appropriate weight,
    avoiding smoking and going for regular
    screenings.
  • Ernest T. Hawk, M.D., M.P.H.
  • Vice President of the Division of Cancer
    Prevention and Population Sciences at The
    University of Texas M. D. Anderson Cancer Center.

30
Prevention
  • Healthy Living

31
Prevention
  • Healthy Living
  • Chemoprevention

32
Prevention
33
Scientific Inquiry
  • 75 Clinical Trials
  • 11 Systematic Reviews
  • Are Being Published Every Single Day
  • Bastian H, Glaszio P, Chalmers I, et al. (2010).
    Seventy-Five Trials and Eleven Systematic Reviews
    a Day How Will We Ever Keep Up? PLOS Med 7 (9)
    e1000326. doi10.1371/journal.pmed.1000326.

34
Journals to Watch
  • New England Journal of Medicine

35
Journals to Watch
  • New England Journal of Medicine
  • Journal of the American Medical Association

36
Journals to Watch
  • New England Journal of Medicine
  • Journal of the American Medical Association
  • Cancer

37
Journals to Watch
  • New England Journal of Medicine
  • Journal of the American Medical Association
  • Cancer
  • Journal of Clinical Oncology

38
Journals to Watch
  • Cancer Research

39
Journals to Watch
  • Cancer Research
  • Clinical Cancer Research

40
Journals to Watch
  • Cancer Research
  • Clinical Cancer Research
  • Cancer Epidemiology, Biomarkers Prevention

41
Journals to Watch
  • Cancer Research
  • Clinical Cancer Research
  • Cancer Epidemiology, Biomarkers Prevention
  • Cancer Prevention Research

42
Journals to Watch
  • Cancer Research
  • Clinical Cancer Research
  • Cancer Epidemiology, Biomarkers Prevention
  • Cancer Prevention Research
  • Molecular Cancer Research
  • Molecular Cancer Therapeutics

43
NEWS FLASH
  • CANCER DISCOVERY

44
NEWS FLASH
  • CANCER DISCOVERY
  • Officially announcing next week

45
NEWS FLASH
  • CANCER DISCOVERY
  • Officially announcing next week
  • Editors in Chief, Jose Baselga, M.D, Ph.D. and
    Lewis Cantley, Ph.D.

46
NEWS FLASH
  • CANCER DISCOVERY
  • Officially announcing next week
  • Editors in Chief, Jose Baselga, M.D., Ph.D., and
    Lewis Cantley, Ph.D.
  • Will be the premier venue for the publication and
    broad dissemination of high impact research in
    all areas of cancer research

47
NEWS FLASH
  • CANCER DISCOVERY
  • Officially announcing next week
  • Editors in Chief, Jose Baselga, M.D., Ph.D., and
    Lewis Cantley, Ph.D.
  • Will be the premier venue for the publication and
    broad dissemination of high-impact research in
    all areas of cancer research.
  • First papers will be published online April 2011

48
NEWS FLASH
  • CANCER DISCOVERY
  • Officially announcing next week
  • Editors in Chief, Jose Baselga, M.D., Ph.D., and
    Lewis Cantley, Ph.D.
  • Will be the premier venue for the publication and
    broad dissemination of high-impact research in
    all areas of cancer research
  • First papers will be published online April 2011
  • In Print July 2011

49
THE ANATOMY OF AN ABSTRACT
  • Conclusions, not titles

50
THE ANATOMY OF AN ABSTRACT
  • Conclusions, not titles
  • Goals

51
THE ANATOMY OF AN ABSTRACT
  • Conclusions, not titles
  • Goals
  • Population Samples

52
THE ANATOMY OF AN ABSTRACT
  • Statistics
  • P Values, anything less than .05 is significant

53
THE ANATOMY OF AN ABSTRACT
  • Statistics
  • P Values, anything less than .05 is significant
  • Hazard Ratios
  • HR1.23, 95 CI, 1.05-1.10

54
THE ANATOMY OF AN ABSTRACT
55
FOLLOW THE NEWS
  • Subscribe to Newswise
  • Check Eurekalert

56
FOLLOW THE NEWS
  • Subscribe to Newswise
  • Check Eurekalert
  • Find a PR Person you trust

57
KEEP IN TOUCH
  • Jeremy Moore
  • Senior Manager, Science Communications
  • Office 267-646-0557
  • Cell 609-519-0212
  • jeremy.moore_at_aacr.org

58
THANK YOU
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