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Stem Cells

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Embryonic stem cells vs. Adult Stem cells Where do adult stem cells come from? ... – PowerPoint PPT presentation

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Title: Stem Cells


1
Stem Cells
2
Remarkable Regeneration!
3
Can humans regenerate body parts?
4
Can humans regenerate body parts?
Think Pair Share If humans have stem cells
but cant grow back certain body parts, but a
lizard can grow back an entire tail, what must be
different between our stem cells and a lizards?
5
Stem Cells
  • Some stem cells are different than others!
  • Stem cells vary in what they can become. Some
    stem cells can only become one type of cell,
    other stem cells can generate an entire organism!

6
Stem Cells
  • Potency
  • Totipotent
  • Pluripotent
  • Multipotent
  • Unipotent

7
Stem Cells
  • Potency
  • Totipotent
  • Pluripotent
  • Multipotent
  • Unipotent

8
Stem Cells
  • Potency
  • Totipotent a stem cell that has the ability to
    divide and produce all the differentiated cells
    in an organism, including the placenta. A
    totipotent stem cell can generate an ENTIRE
    organism!
  • Example cell from morula stage of embryo

9
Stem Cells
  • Potency
  • Totipotent
  • Pluripotent
  • Multipotent
  • Unipotent

10
Stem Cells
  • Potency
  • Pluripotent a stem cell that has the ability to
    divide and differentiate into any fetal or adult
    cell type (but not the placenta). Thus, a
    pluripotent stem cell can differentiate into any
    cell type but cannot become a new organism.
  • Example cell from inner cell mass of blastocyst

11
Stem Cells
  • Potency
  • Totipotent
  • Pluripotent
  • Multipotent
  • Unipotent

12
Stem Cells
  • Potency
  • Multipotent a stem cell that has the ability to
    divide and differentiate into cells of a limited
    range of types.
  • Example Blood stem cell (hematopoietic cell)

13
Stem Cells
  • Potency
  • Totipotent
  • Pluripotent
  • Multipotent
  • Unipotent

14
Stem Cells
  • Potency
  • Unipotent a stem cell that has the ability to
    divide and differentiate into only one type of
    cell.
  • Example Skin stem cells

15
Stem Cells
  • So, what IS a stem cell?

16
Stem Cells
Think Pair Share Think back to the
definitions of potency we just discussed. What
two characteristics do all stem cells have in
common?
17
Stem Cells
  • So, what IS a stem cell?
  • Two defining characteristics
  • Self-renewal Retain the capacity to go through
    many cycles of cell division while remaining
    undifferentiated.
  • Potency Ability to differentiate

18
Stem Cells
  • So, what IS a stem cell?
  • A stem cell is a cell that has the ability to
    self-renew and differentiate along different
    pathways.

19
Embryonic stem cells vs. Adult Stem cells
20
Embryonic stem cells vs. Adult Stem cells
  • Embryonic stem cell stem cell derived from the
    inner cell mass of an embryo.
  • Are pluripotent

21
Where do embryonic stem cells come from???
22
Embryonic stem cells vs. Adult Stem cells
  • Adult stem cell an undifferentiated cell taken
    from a tissue of the body that has the ability to
    divide and differentiate into specialized cell
    types.

23
Where do adult stem cells come from?
  • Usually there is a very small number of stem
    cells in each tissue of body
  • Once removed, limited capacity to divide
  • Scientists trying to find better ways to grow
    large quantities of adult stem cells.
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