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Topics in Coagulation

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Topics in Coagulation Donald M. Voltz, M.D. Assistant Professor of Anesthesiology Case Western Reserve University / University Hospitals of Cleveland – PowerPoint PPT presentation

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Title: Topics in Coagulation


1
Topics in Coagulation
  • Donald M. Voltz, M.D.
  • Assistant Professor of Anesthesiology
  • Case Western Reserve University / University
    Hospitals of Cleveland

2
Pre-Operative
Intra-Operative
3
Coagulation
Anticoagulation
4
Components of Hemostasis
Primary Hemostasis
Endothelial Cells
Coagulation
Fibrinolysis
5
Components of Hemostasis
Primary Hemostasis
6
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7
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8
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9
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10
Components of Hemostasis
Coagulation
11
Coagulation Cascade
12
Coagulation Factors
13
Vitamin K
14
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15
Components of Hemostasis
Fibrinolysis
16
Fibrinolytic Agents
17
Anticoagulants
18
Coagulation Cascade
19
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20
Components of Hemostasis
Endothelial Cells
21
Endothelial Cells
Tissue Factor Pathway Inhibitor
Heparin Sulfate
Thrombomodulin
Endothelial Cell
vWF
t-PA
Adenosine
Nitric Oxide
Prostaglandins
22
Disorders of Coagulation
23
Platelet Disorders
24
Platelet Disorders
Dysfunction
Thrombocytopenia
Hereditary Disorders
25
Factor Disorders
26
Factor Disorders
Acquired Deficiencies
Hereditary Deficiencies
27
Factor Inhibitors
28
Perioperative Anticoagulation
29
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30
Heparin
31
Heparin Mechanism of Action
32
Coumadin
33
Vitamin K
34
Hirudin
35
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36
Asprin
37
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38
Plavix
39
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40
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41
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42
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43
Treatment of Coagulopathy
44
Liver Transplantation
45
Trauma and Massive Transfusions
46
Cardiac Bypass Coagulopathies
47
Antifibrinolytics
48
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49
Disseminated Intravascular Coagulation
50
Plasmin
Thrombin
51
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