SKIN MANIFESTATIONS OF SYSTEMIC DISEASES - PowerPoint PPT Presentation

Loading...

PPT – SKIN MANIFESTATIONS OF SYSTEMIC DISEASES PowerPoint presentation | free to download - id: 6ca756-YzUyZ



Loading


The Adobe Flash plugin is needed to view this content

Get the plugin now

View by Category
About This Presentation
Title:

SKIN MANIFESTATIONS OF SYSTEMIC DISEASES

Description:

SKIN MANIFESTATIONS OF SYSTEMIC DISEASES Dr.MOHAMED NASR Lecturer Of Dermatology & Venereology The relation ... Vesiculobullous dermatitis, periorificial and ... – PowerPoint PPT presentation

Number of Views:4
Avg rating:3.0/5.0
Date added: 8 October 2019
Slides: 46
Provided by: DrMo59
Category:

less

Write a Comment
User Comments (0)
Transcript and Presenter's Notes

Title: SKIN MANIFESTATIONS OF SYSTEMIC DISEASES


1
SKIN MANIFESTATIONS OF SYSTEMIC DISEASES
  • Dr.MOHAMED NASR Lecturer Of Dermatology
    Venereology

2
  • The relation between skin and the body is three
    dimensional
  • A-Effect of skin on the body
  • B-Diseases affecting both the skin and body
  • C-Skin as a mirror of the systemic diseases

3
A-Effect of skin on the body
4
B-Diseases affecting both the skin and body
  • - Connective tissue diseases
  • 1- Systemic lupus erythematosis
  • 2- Systemic sclerosis
  • 3- Dermatomyositis
  • - Hereditary diseases
  • e.g neurofibromatosis (Von Reckling
    Housen's disease).

5
C-Skin as a mirror of the systemic diseases
  • 1-Thyroid disease
  • Both hyper and hypothyroidism are
    associated with characteristic skin
    manifestations.

6
Hyperthyroidism
  • Warm skin, flushing, palmar erythema and
    increased sweating (palms and soles).
  • Fine thin hair and sometimes diffuse alopecia.
  • Plummers nails and thyroid acropachy.
  • Hyperpigmentation.
  • Pretibial myxedema.
  • Pruritus , urticaria.

7
Fine thin hair
Flushing
8
Plummers nails
9
Thyroid acropachy
10
Black halos
11
Pretibial myxedema
12
Hypothyroidism
  • Pale cold ivory yellow scaly wrinkled skin.
  • Absent sweating, dry skin (xerosis).
  • Eczema and pruritus.
  • Palmoplantar keratoderma.
  • Xanthomatosis.
  • Puffy oedema of hands, face and eyelids.
  • Purpura and ecchymoses.
  • Punctuate telangiectasia on arms and fingertips.
  • Delayed wound healing.
  • Brittle striated nails and slow nail growth.
  • Coarse sparse scalp hair.
  • Loss of axillary and facial hair.

13
xerosis
14
Palmoplantar keratoderma
15
Xanthomatosis
16
(No Transcript)
17
2-Diabetes mellitus
  • Diabetic dermopathy is the most common
    manifestation (brownish depressed spots on the
    shins, forearms, thigh and over bony prominences
    ).
  • Erysipelas like erythema on the legs or feet in
    elderly diabetics.
  • Diabetic rubeosis of face , hands and feet.
  • Recurrent cutaneous infections (bacterial ex
    Staph and fungal ex candidiasis).
  • Diabetic bullae and wet gangrene.
  • Diabetic microangiopathy.
  • Diabetic neuropathy.
  • Trophic ulcers and diabetic foot.
  • Pruritus especially perianal and genital regions.

18
  • Skin manifestations associated with diabetes
  • --Necrobiosis lipoidica (pretibial yellowish
    smooth firm atrophic plaque with erythematous
    border and telangiectasia on the surface)
  • --Dessiminated granuloma annulare
  • --Eruptive xanthomas

19
Diabetic dermopathy
20
Necrobiosis lipoidica
21
Dessiminated granuloma annulare
22
3- Gastrointestinal diseases
  • a-Acrodermatitis enteropathica
  • Probably caused by an inherited defect in the
    absorption of zinc leading to acute zinc
    deficiency, usually at the time of weaning.
  • The child becomes photophobic, irritable or
    withdrawn and may suffer from diarrhea.
  • Vesiculobullous dermatitis, periorificial and on
    hands and feet.
  • Loss of scalp hair, stunted growth and higher
    incidence of infection.
  • Poor wound healing.

23
  • b-Ulcerative colitis
  • Skin lesions occur in 10 - 30 of
    patients with ulcerative colitis
  • pyoderma gangrenosum
  • erythema nodosum
  • erythema multiforme
  • aphthus stomatitis
  • urticaria angioedema
  • vascultitis, purpura and gangrene.

24
4- Liver disease
  • Generalized pruritus due to bile salts,
    endogenous opiates
  • Pigmentation
  • jaundice
  • muddy grey hyperpigmentation with yellowish tinge
  • spotted hypomelanosis in relation to spider
    angiomas
  • Spider angiomas and caput medusae
  • Palmar erythema
  • Purpura and bruises
  • Thin hair, female type of hair distribution in
    males and loss of secondary sex characters
    (effect of hormonal disturbance)
  • Terry's nails ( diffuse white colour of the nail
    plate with distal pink colour), white bands,
    clubbing koilonychia
  • Lichen planus

25
Spider angioma
26
Caput medusae
27
Palmar erythema
28
Terrys nail
29
5- Chronic renal failure (uraemia)
  • Muddy brown or grey skin colouration (earthy
    look).
  • Pallor due to reduced erythropoesis and increased
    haemolysis.
  • Dry skin with urea frost and generalised intense
    pruritus.
  • Half and half nails (the distal part of nail
    plate is reddish brown while the proximal part is
    white).
  • Purpura, calcification and perforating dermatoses.

30
Urea frost
31
Half and half nail
32
6- Paraneoplastic lesions
  • They are skin diseases or manifestations which
    have higher incidence with malignancies.

33
  • Lesser Trélat sign sudden development of
    numerous seborrheic keratoses with adenocarcinoma
    of GIT and breast.

34
(No Transcript)
35
  • Pyoderma gangrenosum with lymphomas, leukemias,
    multiple myeloma.

36
  • Dermatomyositis with gynecological tumors in
    women lung cancer in men.

37
  • Acanthosis nigricans with GIT tumors.

38
  • Acanthosis palmaris with bronchogenic carcinoma.

39
  • Palmoplantar keratoderma with carcinoma of the
    eosophagus.

40
  • Acquired icthyosis with lymphomas.

41
  • Pruritis with Hodgkin lymphoma.

42
  • Flushing with carcinoid syndrome.

43
  • Erythroderma with Sézary syndrome, lymphomas and
    leukemias.

44
  • Erythema annulare centrifugum with
    myeloproliferative disorders.

45
(No Transcript)
About PowerShow.com