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Diarrheal diseases

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Title: Diarrheal clisease Author: hy Last modified by: Created Date: 8/18/2000 3:14:46 AM Document presentation format: – PowerPoint PPT presentation

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Title: Diarrheal diseases


1
Diarrheal diseases
????04???? ????2006.6.1
???Pediatrics
2
??General Considerations
  • Definition
  • ???????????????,??????????????

???Pediatrics
3
infectious diarrhea
????
Noninfectious diarrhea
acutelt2? persisting2??2? chronicgt2?
????
mild
??????
moderate
Severe
???Pediatrics
4
??Clinical Findings
Symptom of gastrointestinal
Disturbance of water?electrolyte and acid-base
balance
Diarrhea Vomiting Abdominal pain
  • Dehydration
  • Metabolic acidosis
  • Disturbance of electrolyte

???Pediatrics
5
  • ????????
  • ? ?
    ?
  • ???(???) 5 510
    gt10
  • ?? ????? ????
    ?????
  • ?? ?
    ? ?
  • ??
  • ???? ??? ??
    ??
  • ????? ?? ????
    ????
  • ?? ??
    ???? ????
  • ?? ?
    ??? ?????BP?

6
????????
???? ????
???? ?? 130150mEq/L
lt130mEq/L gt150mEq/L ????
???? ??????? ???/? ????
? ??
??? ???? ?
?? ?? ????
? ???
?? ?? ?
?? ??,???? ?????
?? ??
?? ?? ??
?? ??? ??
? ?
?? ?? ????
?? ?????
7
??????
Hypotonic
(?Nagt??)
?? ?
??
?
??
??
?? ?
? ?
??
?
?
??
????
?????
???? ??\?????
???????
????????
????
?????
???Pediatrics
8
??????
Hypertonic
(??gt?Na)
?? ?
? ?
? ?
?? ?
?? ?
??
??
?? ?
?
?? ??
??
??
???????
????, ????????? ????
???????
??????????
????
????? ? ?
???Pediatrics
9
Summary
  • ??Diarrheal diseases
  • ???????????????,??????????????
  • ???????(6?2?)
  • ?? Clinical Findings
  • 1?????????
  • 2????????
  • 3???????
  • 4????????????? ????

???Pediatrics
10
Metabolic acidosis
  • ??CO2-CP lt 40Vol(17.8mEq/L)
  • ??????CO2-CP lt 25Vol(11mEq/L)
  • ??
  • 1)?????????
  • 2)????,???????????
  • 3)??????????????????
  • 4)?????????????????
  • ????????????
  • ???????????????????(????)

???Pediatrics
11
Hypopotassaemia
  • ??????????????
  • ??
  • 1)????
  • 2)???
  • 3)?????????,????????????
  • ???????????????K???,??????????
  • ?????(??????????)??????????????
  • ?????? ? ????????BP?

???Pediatrics
12
Hypocalcaemia?Hypomagnesaemia
  • ??? (Hypocalcaemia)
  • ???????Ca??????
  • ?????????????,????
  • ??? (Hypomagnesaemia)
  • ???,??????????

???Pediatrics
13
  • ???????,???????,?????????
  • ??????????,?????????????

???Pediatrics
14
??Etiology
  • (?) Predisposing factor(??)
  • ?????????
  • ???????
  • ????

???Pediatrics
15
  • (?) Infectious factor(??)
  • ??????? ?80
  • ??????????????????????????
  • ???????
  • ???????? (EPEC)?????(ETEC)?
  • ???? (EIEC )????? (EAEC)?
  • ???? (EHEC)
  • ??????????????????
  • ??????????????

???Pediatrics
16
  • ???????
  • ????????????
  • ????????
  • ??????????????
  • ??????????
  • ?????????
  • (?????)

???Pediatrics
17
  • (?) Inappropriate of feeding and nursing(10)
  • ???????
  • ???????
  • (?) Food allergy and malabsorption
  • ???????
  • ????????(??????????)

???Pediatrics
18
??Pathogenesis
(?)???(enterotoxin)??
ATP
??? (LT)
??
??? ???
????? ?????
CAMP?
???????
? ?
?? (ST)
GTP
??
??? ???
CGMP?
?????
???Pediatrics
19
  • (?)????????
  • ??????

???????? ????????
?? ??
????
??
???Pediatrics
20
  • (?)????

??????
????
?????
???? (???)
???
?? ????
?? ????
Na?? ??
???Pediatrics
21
  • (?)??????
  • ????

???? ??
?? ????
???? ????
???????
?????
???Pediatrics
22
??Diagnosis
  • ?????
  • ?????????????????????

???? ?? ??
??????? ??????
?? ??? ????
???Pediatrics
23
??differential diagnosis
  • ?????(physiological diarrhea)
  • ?????(bacillary dysentery)
  • ???????(Malabsorption Syndrome)
  • (????????????)

???Pediatrics
24
??Treatment
  • (?)????????????
  • (?)????????????
  • (?)?????????,
  • (?)????,??????

???Pediatrics
25
??prophylaxis
  • (?)??????,????????
  • (?)??????
  • (?)?????????????????
  • (?)???????????

???Pediatrics
26
???????????
  • ??????
  • ?????????
  • ???????
  • ?????????
  • ????????
  • ????????(?????)
  • ?????

???Pediatrics
27
???????????
  • ????
  • ?-???????
  • 624????
  • ?????????
  • ????(??????????)?????????,????
  • ???/??,??/??
  • ?????

???? ?? (rotavirus enteritis)
???Pediatrics
28
???????????
  • ?????
  • ????(?????????)
  • ????,????
  • ?????,????
  • ????????????,????,???
  • ????
  • ??????/??

???? ?? (pathogenic colibacillus enteritis)
???Pediatrics
29
???????????
  • ????????
  • ??????????????
  • ????
  • ?????????????

????? ?? (candida enteritis)
???Pediatrics
30
? ?
??
????
????
? ?
????
? ?
???Pediatrics
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