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Title: TWELFTH INTERNATIONAL ANNUAL CONFERENCE OF OBSTETRICS & GYNECOLOGY AIN SHAMS UNIVERSITY Author: Vaso Last modified by: vasili Created Date – PowerPoint PPT presentation

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Title: Academician Prof/Dr


1
Feto-Maternal Immunologic Dialogue Immunologic
Hypothesis for the Etiology of EPH Syndrome
  • Academician Prof/Dr  
  • Hamdy El-kabarity  M.D.

INTERCONTINENTAL OGASH ACADEMY -
CSPP http//gestosis.ge/eng/26_4.php Ain Shams
Univeristy Cairo  Egypt
WINNER OF ERNST THEODOR RIPPMANN MEDAL DE ONOARE
-2008
PRIZEWINNER OF PROFESSOR IOSEB JORDANIA
INTERNATIONAL PRIZE-2007
2
  • In part I and part II who described the
    immunologic basis for the evolution of EPH
    gestosis .1st described for a syndrome of
    collection of symptoms and signs that occur in
  • Man kind and high apes
  • Only during pregnancy
  • Once it occurs in 1 st pregnancy, it has tendency
    to re -occur in the succeeding pregnancy i.e.the
    1 st pregnancy may be a test of compatability, 
    incompitabaility  of fetus  as an allograft.

3
4. The immunlolgic challenge between the fetus
and placenta as an allograft and his hosting
mother with the  proved  imbalance  of Th1/Th2 -
interleukin 18/12 in normal EPH gestostic
pregnancy.  5. The station  of vascular 
endothelial damage  we all reached  now is not
the final  station more logically pointig to the
changing point to another train.The role of the
father  DNA as foreign  protein  to maternal
immune  systems carried  by the  deported
chorionic villi may lead to the immmunologic
imbalance as the respnose  to this
identification.  6. This  immunologic 
disrupted relation between the mother  and the
placenta and fetus , this may  be to  the picture
of chorionic endothelial damage that mimic to
that appear in the rejected allograft.
4
Also the antiphospholipid  syndrome during
pregnancy of abortion, repeated abortion,
idiopathic placental insufficiency and toxaemias
of pregnancy may be rings of the chain.
http//gestosis.ge/eng/26_5.php
5
90 CME credits Intercontinental Academy of
Medical-Social Sciences (IAMSS) OGASH Number 90
(ninety) IAMSS International CME credits are
recognized by Post Congress IAMSS OGASH Awards
Commission Chairperson, IAMSS Presidium
Chairperson, Hon. Academician of OGASH,
Academician Secretary of OGASH Prof / Dr IRMA de
LUCA BRUNORI MD., PhD. Verified the achievement
award of the proceeding author Hamdy
El-kabarity  Post Congress IAMSS OGASH Awards
Commission Chairman,IAMSS Presidium
Chairperson,Hon. Academician of
OGASHAcademician Prof./Dr. Malkhaz Mizandari
MD., PhD. CERTIFIES The achievement of n. 90
International credits (IAMSS)
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