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MICROBAN OVERVIEW Cipherlab Co. Ltd August 3rd 2010

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Microban Technology: Choice of antimicrobial / test methods / How antimicrobials ... we are up to the challenge In the Home Hospitals, Clinics, Surgeries ... – PowerPoint PPT presentation

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Title: MICROBAN OVERVIEW Cipherlab Co. Ltd August 3rd 2010


1
(No Transcript)
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MICROBAN OVERVIEWCipherlab Co. LtdAugust 3rd
2010
3
Agenda
  • Overview of Microban.
  • Microban Overview Who we are and what we do.
  • Microban Value Proposition How Microban
    creates value for its partners. Why use Microban
    additives?
  • Microban Technology Choice of antimicrobial /
    test methods / How antimicrobials function What
    are the benefits?
  • Microban Support How we help our partners.

4
MICROBAN OVERVIEW
5
Microban International, Ltd.
Microban is the worlds leading provider of safe,
durable and effective built-in antibacterial
solutions.
  • Microban Americas
  • Charlotte, USA
  • Montreal, Canada
  • Sao Paulo, Brazil
  • Mexico City, Mexico
  • Microban Europe
  • Cannock, U.K.
  • Frankfurt, Germany
  • Milan, Italy
  • Barcelona, Spain
  • Microban Asia Pacific
  • Hong Kong
  • Shenzhen, China

6
Microban Manufacturing Warehousing Footprint
Microban supports customers on a regional level
with local manufacturing and export of its
additive systems, and is expanding its
manufacturing base to Asia.
  • North America
  • Charlotte, USA (Polymers Formulations)
  • Export to EU, Central South America, and Asia
    (Polymers Formulations)
  • Europe
  • Liverpool, U.K. (Polymers)
  • Asia Pacific
  • Hong Kong Warehouse (Polymers Formulations)
  • Shenzhen, China
    (Polymers)

7
BUILT-IN TO MORE THAN 750 PRODUCTS BY OVER
150 LEADING MANUFACTURERS AROUND THE WORLD
8
Microban Partners - Selection
Microban is privileged to help these and other
industry-leading companies around the world
improve and differentiate their products.
9
Our impressive reach towards consumers
  • Microban we are up to the challenge
  • In the Home
  • Hospitals, Clinics, Surgeries
  • Hotel, Restaurants, Catering Venues
  • Offices, Waiting Rooms, Care Homes
  • Supermarkets, Shopping Centres
  • Other Public Venues
  • Airports, Public Transport Venues
  • Gyms, Leisure, Pools Spa Centres
  • Museums, Schools, Universities
  • and, we are looking at new areas all of the
    time...

10
Example product materials we already treat
11
MICROBAN VALUE PROPOSITION
12
Microban Value Proposition
We help our partners strengthen their businesses
by creating a valuable point-of-differentiation
for their products through a compelling
ingredient brand.
For companies trying to strengthen their businesses and address core business challenges. Microban represents an alternative business strategy that brings value by providing a compelling and enduring point of product differentiation And we do this by providing a complete ingredient brand solution including For companies trying to strengthen their businesses and address core business challenges. Microban represents an alternative business strategy that brings value by providing a compelling and enduring point of product differentiation And we do this by providing a complete ingredient brand solution including
The leading antimicrobial brand Innovative technical solutions Patent protection (when available) Regulatory support Ingredient branding marketing expertise
13
The power of Microban ingredient branding
Since 1996, Microban have been driving consumer
product sales through innovation, improved
quality, product longevity enhanced consumer
appeal
  • Extend Product Life The life of a product will
    be extended when using Microban we restrict
    typical microbial and fungal degradation
  • Visible Cleanliness Product cleanliness is
    improved with our antimicrobial and / or
    antifungal solution
  • Invisible Cleanliness Microbes are invisible.
    Their growth is proven to be significantly
    controlled by Microban technology
  • Odour Reduction Microbes can cause noxious
    odours. Using Microban naturally reduces odours
    and improves product appeal for consumers

14
MICROBAN TECHNOLOGY
15
Microban Technology
  • Plastics
  • Antimicrobial is incorporated during extrusion
    for thermoplastics or by addition to liquid resin
    for thermosets
  • Full range of plastics, from polyolefins to
    polystyrenes and polycarbonate to unsaturated
    polyesters and acrylics
  • Textiles
  • Incorporated via standard textile processes such
    as the dye bath or in surface finishes such as
    softeners and permanent press finishes
  • Coatings
  • Mixed with latex or solvent-based resins
  • Addition rates into the coating depend on the
    application rate of the coating on the substrate
  • Ceramics
  • Secondary glaze on tile surfaces
  • Metals
  • Epoxy powder coatings or nickel / chrome
    electroplating

16
Choice of Antimicrobial
  • The available choices for antimicrobials will
    depend on
  • Efficacy desired
  • Antibacterial
  • Anti-fungal
  • Processing
  • Process conditions, particularly temperature
  • Materials used for part
  • Properties desired (e.g, clarity)
  • Cost
  • Regulatory approvals
  • Approval for specific use
  • Food water contact approvals, if needed for
    water.
  • Approved use limits

17
Benefit Improved Cleanliness
  • Does not necessarily lead to sterile surfaces
  • Provides continuous action as compared to
    disinfection
  • Does not readily transfer to skin, food, or
    other contact surfaces

18
Effect of Disinfection
19
Effect of Antimicrobial Treatment
20
Antimicrobial Treatment vs. Disinfection
Disinfectants
Microban Antimicrobial Technology
21
Microban Efficacy Demonstration
Unprotected Surface
2 hours
16 hours
20 hours
24 hours
Surface with Microban Antimicrobial Protection
2 hours
16 hours
20 hours
24 hours
This information is based upon standard
laboratory tests and is provided for comparative
purposes to substantiate antimicrobial activity
for non-public health applications. Microban
technology is not designed to replace good
hygiene practices or protect users from disease
causing microorganisms. Antimicrobial action
limited to product surface.
22
Antibacterial Test Methods
  • Qualitative Test Method
  • 3 main methods covering bacterial and Fungal
    resistance.
  • AATCC TM 30 pt III (plastics materials Fungal
    growth)
  • AATCC TM 147 (bacterial test method mainly for
    textile materials)
  • Kirby Bauer / Zone Diffusion (plastics materials
    bacterial growth)
  • Results expressed as a Zone of Inhibition or
    measurement of inhibition area (mm).
  • Observations are also noted for Surface growth
    (fungal tests) and graded according to
    coverage
  • Qualitative test methods show a product is able
    to inhibit the growth of the test organism
    (bacteriostatic or fungistatic activity)

23
Antibacterial Test Method Summary
  • Quantitative Test Method
  • Two main standards employed
  • ISO 22196 / JIS Z 2801 (Japanese Industrial
    standard)
  • AATCC TM 100
  • Results expressed as a reduction value and Log
    Kill e.g. 99.9 3 Log reduction after recovery
    of viable organisms following a 24hr period.
  • Samples results are expressed verses the initial
    population of bacteria or verses untreated
    control (when available)
  • Quantitative test methods show a product is able
    to actively kill the test organism (bactericidal
    or fungicidal activity)
  • Results obtained will also distinguish between
    bacteriostatic and bactericidal activity.

24
Antibacterial Microban Actives Mode of Action
  • CHLOROPHENOXY
  • ANTIMICROBIALS
  • Multiple routes
  • Combine with protein/enzyme amino acids and
    disrupt the cellular functions
  • Disrupt cell membrane integrity causing loss of
    ion transport gradients
  • Triclosan blocks lipid biosynthesis and prevents
    formation of vital membrane fatty acids
  • Metal ions
  • Copper or Silver ions combine with the thiol
    (-SH) groups in amino acids and disrupt enzyme
    catalysis and function
  • Zinc Pyrithione Based Antimicrobials
  • Disrupts normal ion transport gradients,
    interfering with nutrient intake and energy
    production. Metal ions in the cell are chelated
    and transported out of the cell
  • Cationic Antimicrobials
  • Disrupts ion transport gradients across the cell
    membrane interfering with cellular respiration
  • React with enzymatic functional groups

25
Claims Overview
  • Claims will be developed based on laboratory
    substantiation of bacteriostatic/bacterocidal
    and/or fungistatic/fungicidal efficacy.
  • In addition, claims will be formulated based on
    one or more of the following key functional
    benefits provided by Microban protection.
  • Invisible Cleanliness
  • Visible Cleanliness
  • Odour Control
  • Product Degradation
  • Microban antimicrobial technologies are designed
    to provide durable antimicrobial protection.
    Lifetime durability claims may be used with the
    appropriate substantiating data.

26
Case Study Cosentino
The makers of Silestone countertops embraced
Microban protection to differentiate their
product from other quartz surfaces and to steal
share from other countertop surface materials.
  • Primary Objective
  • To differentiate Silestone from granite and
    other countertop materials to generate demand and
    justify premium price.
  • Actions
  • Launched worldwide across their entire product
    line and supported with heavy media (T.V.
    advertising at prime time on Spanish and
    Portuguese channels) and pan European consumer
    print campaigns.
  • Sponsorship of Fernando Alonso Formula One
    driver supported by TV advertising on Spanish and
    Portuguese channels.
  • Results
  • Major growth across Europe leading to 9 new sales
    offices and 3 distribution warehouses opening.
  • Extension of product diversity from kitchen
    countertops to public space interior design.

27
Application example Hospital Design
  • 1. Walls
  • 2. Beds and curtains
  • 3. Blinds
  • 4. High contact surfaces
  • 5. Flooring
  • 6. Switches and controls
  • 7. Wet environments
  • 8. Computer equipment and reception areas

Infection risk control protecting buildings
28
Case Study WHIRLPOOL
Whirlpool embraced Microban to enhance their
appliances features and is currently broadening
the range of treated components across the product
  • Primary Objective
  • To enhance Whirlpool appliances with a range of
    antibacterial features.
  • Action
  • Whirlpool have introduced a special air filter
    device in the refrigerators which incorporates
    Microban antibacterial technology.
  • Following its success, the Microban technology
    has been extended to additional areas within the
    refrigeration project and also across the product
    mix (dishwashers and washing machines) within the
    Whirlpool and Bauknecht brands.
  • Results
  • Significant differentiation achieved and
    communicated to Whirlpool customers.
  • Market surveys showing a remarkably high
    percentage of Whirlpool customers find the
    treatment appealing and innovative.

29
MICROBAN SUPPORT
30
The Microban Solution
Microban provides a turnkey, ingredient branding
solution, that ranges from a technical solution
through the use of the Microban brand.
31
Technical Support
Microban provides industry-leading technical
services to ensure that partners get a customised
technical solution that best meets their unique
product.
  • Expert research and development dedicated staff
    of engineers, microbiologists and analytical
    chemists.
  • The only antimicrobial solutions provider that
    offers over 20 different antimicrobial
    technologies under a single umbrella brand.
  • One of the most advanced antibacterial
    laboratories in the world.
  • Bacterial and fungal microbiology laboratories
    on-site at HQ in North Carolina.
  • Capacity to manage all of our partners testing
    needs. Microban micro lab completes over 30,000
    tests annually.
  • Close liaison with independent testing
    laboratories across Europe.
  • Privileged to be conducting cutting edge
    antimicrobial product development for the US
    Department of Defence.

32
HEALTHCARE RESEARCH
33
Healthcare Research
  • 97 of healthcare professionals are concerned
    about the presence of microbes (such as bacteria,
    mold and mildew) in their healthcare facilities.

34
Healthcare Research
  • 79 of patients are concerned about the presence
    of bacteria when at a hospital.

35
Patient room products / medical devices
  • From initial patient and healthcare provider
    research Microban has identified key areas of
    contamination within patient rooms
  • This research is being supported by a patient
    room swab study within Presbyterian Hospital
    Huntersville, USA to confirm highly contaminated
    products - hot spots
  • Microban is currently in dialogue with
    manufacturers of hot spot products and more
    than half have expressed a high level of interest
    in engaging with Microban on a project

36
Patent Protection
With one of the strongest antimicrobial patent
positions in the world, Microban helps its
partners create competitive barriers where
possible.
  • 163 patent applications and 42 issued patents
    protecting the use of Microban antimicrobials in
    various end products help provide effective
    barriers to entry by your competitors.
  • In-house patent attorney surveys patent landscape
    at the outset of the project to determine areas
    of opportunity for patent protection.
  • Protects our partners from infringing on 3rd
    partys rights as well.
  • Proactive patent stance enables us to preserve
    our partners exclusivity and provide market
    leverage.

37
Regulatory Support
Microban regulatory helps partners quickly secure
the necessary approvals to hasten product
launches, and ensures aggressive claim compliance.
  • In-house VP, Regulatory Affairs with over 20
    years of regulatory and toxicology experience
    provides partners with unmatched expertise.
  • Former EPA Director is a member of the Microban
    Board who provides on-going advice.
  • Washington Brussels based regulatory
    consulting / law firms support Microban and its
    partners on a regular basis.
  • Experience working with international regulatory
    authorities to ensure compliance on a global
    basis.
  • US - EPA, FDA - EU - ECHA
  • Canada PMRA - Australia - AVMPA
  • Mexico Cicoplafest - UK HSE
  • Facilitate third part approvals with agencies
    such as NSF and TUV.

38
MARKETING SUPPORT
39
Microban Marketing Support
  • Claims Development
  • Packaging Development
  • Point of Sale Development
  • Market Research
  • Press Releases
  • Sales Training
  • Microban Website
  • Microban Collateral
  • Customer Specific Programmes
  • Website Development

40
Microban Partner Advertising
41
Healthcare microsite
www.microban.com/partnersites/microban-medical
42
Microban website
World-wide coverage with direct link to partner
website
43
Microban support literature
Generic, customized and multilingual designed
for events, press packs and trade shows
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