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NEW FACULTY ORIENTATION

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NEW FACULTY ORIENTATION. Introduction to the UMSOM. Research Enterprise. Richard N. Pierson III, MD, FACS. Senior Associate Dean for Academic Affairs – PowerPoint PPT presentation

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Title: NEW FACULTY ORIENTATION


1
NEW FACULTY ORIENTATION
  • Introduction to the UMSOM
  • Research Enterprise
  • Richard N. Pierson III, MD, FACS
  • Senior Associate Dean for Academic Affairs
  • Interim Director for Research Affairs
  • October 23, 2012

2
SOM Research Faculty Funding
  • Total Faculty Research Productivity
  • National Avg. 315K/PI
  • UMB Avg. 500K/PI 8th most productive nationally
  • AAMC National Ranking
  • 5th among 76 public medical schools
  • 16th among 138 public and private medical
    schools
  • Total Grants and Contracts Expenditures

3
NIH Funding Profile of Current SOM Research
Faculty
  • PROGRAM PROJECTS (5)
  • HYPERTENSION
  • CARDIAC SIGNALING
  • VASCULAR SIGNALING
  • MENTAL RETARDATION
  • ALTERNATIVE MEDICINE
  • CENTER GRANTS (5)
  • PSYCHIATRIC INTERVENTIONS
  • AGING
  • HEALTH DISPARITIES
  • NCI DESIGNATED CANCER CENTER
  • NUTRITION OBESITY RESEARCH

4
NIH Funding Profile of Current SOM Research
Faculty
  • TRAINING GRANTS (16)
  • TOXICOLOGY/EPIDEMIOLOGY
  • CELLULAR NEUROSCIENCE
  • MEMBRANE BIOLOGY
  • IMMUNITY AND INFECTION
  • MUSCLE BIOLOGY
  • INTEGRATIVE NEUROSCIENCE
  • OROFACIAL BIOLOGY/NEUROSCIENCE
  • CARDIOVASCULAR CELL BIOLOGY
  • REHABILITATION RESEARCH
  • TRANSFUSION MEDICINE
  • CANCER BIOLOGY
  • VASCULAR BIOLOGY

5
NIH Funding Profile of Current SOM Research
Faculty
  • TRAINING GRANTS/CLINICAL FIELDS
  • GASTROENTEROLOGY
  • SCHIZOPHRENIA
  • VACCINOLOGY
  • GERONTOLOGY/EXERCISE PHYSIOLOGY
  • TRAUMA
  • EPIDEMIOLOGY OF AGING
  • MEDICAL SCIENTIST (MD/PhD)
  • IN-PROGRESS
  • REPRODUCTIVE BIOLOGY
  • CHEMOSENSORY NEUROSCIENCE
  • MOLECULAR SIGNALING/STRUCTURE
  • MICROBIOLOGY/IMMUNITY

6
SOM Organized Research Centers
  • Health Policy Health Services Research
  • Integrative Medicine (CIM)
  • Mucosal Biology
  • Research on Aging
  • Shock, Trauma and Anesthesiology (STAR)
  • Stem Cell Biology Regenerative Medicine
  • Vaccine Development (CVD)
  • Vascular and Inflammatory Diseases (CVID)
  • (Bioinformatics in development)

7
SOM Programs
  • Comparative Medicine (Vet. Resources)
  • Genetics and Genomic Medicine
  • Minority Health and Health Disparities
  • Neuroscience
  • Oncology
  • Personalized Medicine
  • Trauma

8
Structural Biology Network
  • NMR Center (Center for Biomolecular Therapeutics)
  • X-ray Crystallography Core
  • Mass Spectrometry Core
  • Proteomics Core (SOM, SOP)
  • Edman Sequencing and Protein Analysis Core
  • BiaCore Core Facility
  • Protein Production and Purification

9
Drug Development Network
  • Pharmacokinetics Biopharmaceutical Laboratory
  • Industrial Pharmaceutics Laboratory
  • Clinical Pharmacology Unit
  • Center for Nanomedicine and Cellular Delivery
  • Computer Aided Drug Design
  • High-throughput Screening Core
  • Center for Biomolecular Therapeutics (SOM at
    Shady Grove)

10
UM Institute of Human Virology (IHV)
SOM Institutes
UM Institute for Genome Sciences (IGS)
Dr. Claire Fraser Director, Institute for Genome
Sciences Professor, Department of Medicine
Robert Gallo, MD
Director, Institute of Human Virology Professor,
Department of Medicine
Excludes the newly established Clinical and
Translation Science Institute (CTSI)
11
Efforts to Enhance Research Opportunities Office
of Research Career Development
  • Target Audiences
  • New Faculty (junior principle investigators)
  • Post-doctoral research scientists
  • First Priority - to develop workshops, classes
    and consultation services focusing on
  • - Writing a Competitive Grant Application
  • - Revising a Grant Application
  • - Individual mentoring
  • - Identifying Funding Opportunities
  • Wendy Sanders, Derek Haseltine, Stacy Small

12
Basic and Clinical Resources Network
  • NICHD Brain/Tissue Bank for Developmental
    Disorders
  • Pathology Biorepository and Research Core
  • Maryland Psychiatric Research Centers Brain Bank
  • Histology Core
  • Biostatistics Shared Resource (Epi/PH)
  • Informatics Resource Center
  • Pharmaceutical Research Computing
  • BIORESCO (Biomedical Research Supply Core)

13
Support for Enhanced Clinical Research
  • Dept of Epidemiology/PH
  • Statistics, biocomputation, study design, mock
    review (Jay Magaziner)
  • IRB (HRPO) - (Susan Buskirk)
  • CICERO assistance with submission
  • Electronic systems submission --
  • COEUS grant submissions review (ORD)
  • Conflict of Interest review- (Nancy Lowitt)
  • IACUC protocol review (Peiser/Sacci)
  • Planned CTSA (GCRC, K12) (Davis/Shuldiner)

14
Infrastructure to Enhance Research Environment
  • Genomics and other omics cores
  • Small Animal Physiology core
  • Vet services and facilities review
  • Animal Imaging Center (6 HH )
  • 7T MRI, CT/PET, Ultrasound TEM/SEM
  • Confocal microscopy (6 HH)
  • Flow Cytometry, sorting
  • GLP capability (Vet Med)
  • GCP (Personalized Medicine)
  • Deans office personnel and support for complex
    grant preparation, submission and management
  • Seed funding and Bridge funding

15
UMB / UMCP Collaboration M-Power Maryland
A new Institutional collaboration to maximize
research and expertise across campuses for the
benefit of the faculty, state and citizens of
Maryland.
16
UMB UMCP Funding and Joint Seed
Programs
  • FY2012 Total Grant Contract Funding
  • UMB approx. 500 million
  • UMCP approx. 500 million
  • Significant Economic Impact for the State
  • UMB-UMCP Joint Seed Program
  • FY2007-2011 Funded 38 grants totaling 2.8M
  • New SEED programs in 2012
  • CBT/IBBR (300K) , CTSI (150K)
  • Important Resource for future federal and
    non-federal research proposals

17
University of Maryland School of Medicine
Available Core Facilities and Shared Resources
Imaging Network Confocal Microscopy Electron
Microscope Animal Imaging MRI Research
Imaging Neuroimaging
Clinical Resources Network Pathology
Biorepository Brain Tissue Banks Cytokine
Hormone Immunoassay Core Flow Cytometry
Structural Biology Network NMR X-Ray
Crystallography Proteomics/Mass Spec.
Biacore Edman Sequencing
Drug Development Network Pharmacokinetics/Biopharm
aceutics Lab Industrial Pharmaceutics Lab Center
for Nanomedicine and Cellular Delivery Computer-Ai
ded Drug Design (CADD) High Throughput Screening
Core
Model Development Network Novel Model Systems
Development Veterinary Services Translational
Core Lab Small Animal Physiology Core
Bioengineering Biorobotics Network UMCP
Genomics Network Biopolymer/Genomics
Core Genomics Resource Center Biochemical
Genetics Lab Cytogenetics Lab Translational
Genetics Core
18
Core Facility Director
Confocal Microscopy Tom Blanpied
Electron Microscopy Ru-ching Hsia
Animal Imaging Rao Gullapalli
MRI Research Imaging Rao Gullapalli
Neuroimaging Will Carpenter
NMR David Weber
X-Ray Crystallography Eric Toth
Biacore Robert Bloch
Edman Sequencing/Protein Analysis Brian Hampton
Pathology Biorepository Olga Ioffe
Developmental Brain Bank Ron Zielke
Cytokine Lab Jeff Hasday
Flow Cytometry (CVD) Marcelo Sztein
Flow Cytometry (UMGCC) Ferenc Livak
High Throughput Screening Core Paul Wilder
Veterinary Resources Louis Detolla
Translational Core Lab Rena Lapidus
Small Animal Physiology Core Ling Chen
Transgenic/Novel Model Systems Valerie Stewart
Biopolymer/Genomics Core Nick Ambulos
Genomics Resource Center Lisa Sadzewicz
Biochemical Genetics Lab Mimi Blitzer
Cytogenetics Lab Yi Ning
Translational Genomics Lab Nick Ambulos
Imaging
Structural Biology
Clinical Resources
Drug Development
Model Development
Genomics
19
NIH Construction Grant Space Renovations BRB-7,
HH and HSF1-6
  • Renovations to BRB-7 will provide new space for
    research core facilities (Flow Cytometry, Mass
    Spectrometry, Biopolymer, Transgenic), Clinical
    Cytogeneics, and a CLIA-certified Personalized
    Genomics core with robotic sample archive.
  • Renovations to the 6 floor of HSF1 and HH will
    provide renovated research space for consolidated
    imaging cores (Electron Microscopy, Confocal
    Microscopy, in vivo animal imaging, MRI, PET-CT,
    ultrasound).
  • Anticipated completion date is summer, 2013.

20
NIH Core Renovation and Consolidation Grant BRB-7
Renovations to BRB-7 include an open lab design
for the north side (top), which will physically
consolidate a number of existing core facilities
such as Biopolymer, Transgenic, translational
Lab, BIACore, Proteomics, and others. The south
side (bottom), will allow development of new
resources that will specifically support clinical
and translational research. Estimated date for
completion August, 2012.
21
NIH Core Renovation and Consolidation Grant BRB-6
Proposed renovations to BRB-6 will result in a
comprehensive imaging suite between BRB and
Howard Hall 6th floors. This will include
Electron Microscopy, Confocal Microscopy and
whole animal imaging (MRI, PET/CT).
22
Research Environment - Space Management
  • Existing Space allocation annual reassessments
    for productivity
  • Dry lab space lease commercial building space
  • Wet lab space renovate and repurpose labs
  • New HSF III (2018) 178,000 NASF Planning and
    Design started
  • Building and Leasing UMB Biopark Ongoing
    development potential

23
Closing
  • Seek out the tools to help you advance
  • Manage the space available wisely
  • Use the expertise and collaborative spirit of the
    faculty to help guide you
  • Take advantage of all of these highly productive
    and leveraged resources for success
  • Communicate with mentors and peers often
  • Enjoy your experience in SOM and use your time
    well to contribute to the community
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