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Title: furan


1
?13?
2
?????????????
3
???
5???
4
3
4
3
3
4
2
5
2
5
2
5
1
1
1
??
??
??
furan
thiophene
pyrrole
4
3
4
3
3
4
2
5
1
1
2
5
2
5
1
??
??
??
thiazole
pyrazole
imidazole
??
???
?
?
isoxazole
oxazole
4
(No Transcript)
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????
4
4
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4
5
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3
6
5
3
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2
1
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2
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7
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8
1
1
??
???
??
quinoline
isoquinoline
indole
??
?
acridine
3-??-2-???
(ß-??-a-???)
6
ß-????
(??????)
ß-?????
(????????)
N-??-5-????
5-????
7
4H-??
2H-??
7H-??
9H-??
(?????)
(????)
8
??5?6??????
1. ???
p?? 6(??4n2??)
???
9


??
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p?? 6(??4n2??)
???
10
??????(????)
?????????????????
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ß
(20)
????????????????
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2. ???
13
-
(??)


pKb 7.1 2.5
17.5
14
?????3???????????
??
? gt ? gt ?
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3. ???????
??
pKb2.8
pKb8.8
?
16
???????
???
????
???
??
(C) (U) (T)
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??
???
???
(A) (G)
???
????
??
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??
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?????
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????
??????
RNA
DNA
??
??
??? ??? ???? ???
??? ??? ??? ???
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??????????(NAD)
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??????????????
???
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??
??????????????????????????
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???(?????)
???
???
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?????
????(SD)
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????
670pm
690pm
230pm
240pm
??????
????????
?????
??????
???
????
25
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