Local hemodynamic

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Local hemodynamic disorders
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2010.09.28
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review

• Thrombosis and thrombus
• Elements in thrombosis
• Morphology and types of thrombi
• Consequence of thrombi
• Influence of thrombi on human body

??(embolism)
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Embolism ??
Embolism is the occlusion or obstruction of a
vessel by an abnormal mass (solid, liquid, or
gaseous) transported from a different site by
the circulation. The abnormal mass is embolus)
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thrombi, fatty droplets, gas, Amniotic fluid,
tumor cells
Types of emboli
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Motional pathway of embolus
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crosses embolism
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Retrograde embolism
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(No Transcript)
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???? Thromboembolism
pulmonary thromboembolism
95 originate from deep leg vein thrombi above
the knee
deep leg veins
????? Saddle embolism
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pulmonary thromboembolus
Types and consequence
---Depends on size and numbers
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pulmonary thromboembolus
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Thromboembolism ????
??????? Systemic thromboembolism

• Origin--Valvular vegetation(????????????????)
• --mural thrombus (????????????,??,??
  )
• Location Lower extremities(75),brain(10),
• intestines, kidneys, spleen
• Consequence infarct

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Thromboembolism ????
??????? Systemic thromboembolism
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Fat embolism????
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Fat embolism????
??gt20µm????--?????,??????
??lt 20µm???????????? ??????????
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Gas embolism ????
?????????????????????????,?????????,??????(gas
embolism) ???????(air embolism) ??????????????????
?????????????,????(decompression sickness)
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(No Transcript)
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Amniotic fluid embolism ????
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Bacterial embolism????
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Embolism of tumor cell
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Infarction ??

• Definition An infarct is an area of ischemic
  necrosis caused by occlusion of either the
  arterial supply or the venous drainage in a
  tissue or an organ.

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Infarction ??
Causes of infarction

• ????????,?? (99)
• Thrombosis, Embolic occlusion
• ??????
• Vessel compressed
• ????
• Spasm of arteria

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??????? Factors that influence the development of
infarction
??????? Occlusion of the arteries
Also depends

• ???????
• Nature of the vascular supply

• ?????????
• Rate of development of occlusion

• ????????????
• vulnerability to hypoxia

• ??????
• Oxygen content of blood

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Morphology of infarct
1????????????????
organ shape type nature of
infarct kidney spleen lung heart
intestine brain
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Morphology of infarct
???
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Morphology of infarct
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Morphology of infarct
?????--?????,????? ?????--?????,???????
2???????
organ shape nature of infarct color of
infarct kidney Spleen lung Heart intestine
brain
????? coagulative necrosis
????? Liquefactive necrosis
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Morphology of infarct
3?????????????
organ shape nature of infarct color of
infarct kidney Spleen lung heart intestine brain
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Types of infarct

• ????? anemic infarct (white infarct )
• arterial occlusion
• in solid tissue spleen, kidney, heart, brain

Infarct of kidney
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Types of infarct
????? anemic infarct (white infarct )
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Types of infarct
????? hemorrhagic infarct (red infarct)
????

• previously congested
• ????
• in loose tissues lung, intestine
• ????
• with dual circulations lung, small intestine
• ????
• with venous occlusions ovarian torsion
• ?????

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Types of infarct
????? hemorrhagic infarct
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Types of infarct
??????
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Types of infarct
?????? Hemorrhagic infarct of small intestine
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????? (septic infarct)
??????? infective endocarditis
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Effect and consequence of infarct
Tissue and organ Size, sites With infection
Effects
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Effect and consequence of infarct
Organization?Scarring Liquefaction
Consequence
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