mRNA Transport

1
mRNA Transport
2
Translation
Three stages of translation ?Initiation -
Recruitment of mRNA to the ribosome ?Elongation -
Synthesis of nacent polypeptide ?Termination -
Release of polypeptide from the ribosome
initiation
termination
elongation
3
Triplet code
The coding dictionary
4
Translation The Players
Messenger RNA (mRNA)
5
Translation The Players
Ribosome Structure
Transfer RNA (tRNA)
6
Amnioacyl tRNA Synthetases
tRNA charging
7
Translation The Players
The Ribosome
8
Translation in Eukaryotes
Much more complex!
Eukaryotes 80S 40S and 60S 1 and 3
33 and 49 processed Kozak consensus Many
14 2 2
9
Translation in Eukaryotes
Much more complex!