Title: Outcomes with dual RAAS inhibition with an ACE inhibitor and ARB vs standard therapy in patients on hemodialysis with CHF standard therapy in patients on hemodialysis with CHF
1Outcomes with dual RAAS inhibition with an ACE
inhibitor and ARB vs standard therapy in patients
on hemodialysis with CHF standard therapy in
patients on hemodialysis with CHF
End point ACE plus ARB Standard therapy p
All-cause mortality () 58.3 73.1 lt0.001
CV death () 39 49.3 lt0.001
CHF hospitalization () 37.7 68.4 lt0.0001
Cice G et al.The XLII ERA/EDTA Congress June
4-7, 2005 Istanbul, Turkey.
2Reductions in proteinuria with enalapril,
losartan, or the combination at 12 weeks in
kidney-transplant patients
End point Enalapril Losartan Enalapril plus losartan
Decrease in proteinuria () 17.6 17.3 27.2
Tuncer MA et al. The XLII ERA/EDTA Congress June
4-7, 2005 Istanbul, Turkey.