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Title:

Digitalis in Cardiovascular Treatments

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... William Withering Ten years research Dropsy Foxgloves influence How it Works Cardiac Glycosides Sodium-Potassium Pump Increasing Cardiac ... – PowerPoint PPT presentation

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Title: Digitalis in Cardiovascular Treatments


1
Digitalis in Cardiovascular Treatments
  • Presented By Lauren Stewart

2
What is Digitalis?
  • Genus of 20 species
  • Perennial
  • Scientific name finger like
  • Common Foxglove

3
Normal Life Span
  • Biennial
  • Year one Leaves, Stems, Roots
  • Year two Flowers, Seeds

4
Native
  • Europe
  • West and Central
  • Asia
  • North West Africa
  • Wildflowers

5
Varieties of Foxgloves
  • 6 colors
  • 2-6 feet in height
  • 18 inches width

6
Varieties of Foxgloves
  • Smallest Yellow Foxglove
  • Largest Rusty Foxglove
  • Over five hybrids

7
Discovery
  • William Withering
  • Ten years research
  • Dropsy
  • Foxgloves influence

8
How it Works
  • Cardiac Glycosides
  • Sodium-Potassium Pump
  • Increasing Cardiac Contractility (positive
    inotrope)

9
Medical Uses
  • Slow Muscular Dystrophy
  • Reducing Pressure in Eye of Glycoma Victim
  • Congestive Heart Failure (CHF)

10
Congestive Heart Failure
  • 5 Million People in United States
  • 550,000 new cases per year
  • Diastolic
  • Systolic

11
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12
Active Chemicals
  • Extracted from Leaf
  • Digitoxin
  • Digoxin
  • difference

13
A time for Picking
  • Second Year
  • Only perfect green leaves
  • Dry weather

14
Toxicity
  • Entire Plant
  • Anorexia, Nausea, Vomiting, Diarrhea
  • Further Heart Problems
  • Toxins dont die with plant

15
Additional Names
  • Witches Gloves
  • Dead Mens Bells
  • Bloody Fingers
  • Fairy Caps
  • Folks Glove

16
Negative Feedback
  • Less effective
  • Excessive build up
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