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Biosensors

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Anthony Catalano Any device that analyzes a biological compound into a measurable signal Composed of a bioreceptor, transducer, and an electronic peripheral ... – PowerPoint PPT presentation

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Title: Biosensors


1
Biosensors
  • Anthony Catalano

2
What are Biosensors?
  • Any device that analyzes a biological compound
    into a measurable signal
  • Composed of a bioreceptor, transducer, and an
    electronic peripheral

3
Composition of Biosensors
  • Bioreceptor Part of device that interacts with a
    biological material to identify and interact with
    a target molecule
  • Transducer Part of the device that turns the
    target molecule into a measured signal
  • Electronic Peripheral Turns the measured signal
    into a graphical user interface (GUI) utilizing
    microprocessors
  • Enzymes, Antibodies, or nucleic acids.
  • Piezoelectric, Thermal, Electrochemical, and
    Optical
  • LED Display

4
Transducers
  • Piezoelectric crystal detector uses the change
    of frequency to calculate change in mass
  • Thermal measures change in heat (exothermic,
    endothermic)
  • Electrochemical (Amperometric, or
    potentiometric) uses electrodes to measure
    current
  • Optical uses Surface Plasmon Resonance (SPR), or
    reflectance to identify various biological
    molecules
  • Measures Mass
  • Measures heat, requires large sample size,
    complicated devices
  • Amperometric are among the most common
    transducers for biosensors
  • Great for identifying antigens, or cancerous
    cells in a solution

5
Current Applications and Areas of Improvement
  • Current Applications
  • Lab-on-a-chip
  • Pollutant Control
  • Patient Diagnosis
  • Detection of harmful pathogens, bacteria, toxic
    compounds
  • Future
  • Disposable
  • Low Cost
  • Increased Sensitivity
  • Improved Microprocessors
  • Multipurpose
  • Environmental friendly

6
Resources
  • 1. Pohanka, Miroslave. "Electrochemical
  • Biosensors Principles and Applications."
  • Journal of Applied Biomedicine (2008) 58-62.
  • Web. 20 Nov. 2012.
  • 2. Mutharasan, Raj. "Biosensors." Engineering
  • Biotechnology. N.p., n.d. Web. 20 Nov. 2012.
  • lthttp//www.gatewaycoalition.org/files/Hidde
  • n/sensr/ch1/1_1f.htmgt.
  • 3. Kumar, Ashok. "Biosensors Based on
  • Piezoelectric Crystal Detectors Theory and
  • Application." Department of Mechanical
  • Engineering and Center for Microelectronics
  • Research (2010) 1-6. Web.
  • http//www.tms.org/pubs/journals/JOM/0010/
  • Kumar/Kumar-0010.html
  • 4. Dey, D., and T. Goswami. "Optical Biosensors
  • A Revolution Towards Quantum Nanoscale
  • Electronics Device Fabrication." Journal of
  • Biomedicine and Biotechnology 2011.348218
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