Rapid screening and identification of illegal Drugs by IR Absorption spectroscopy and

1
Rapid screening and identification of illegal
Drugs by IR Absorption spectroscopy and gas
Chromatography (DIRAC)
S. Zampolli, I.Elmi, GC.Cardinali
Theme 10 Security, Cooperation Programme Topic
SEC-2009.1.3.2 Drug precursors Proposal
242309 Proposal deadline 8 dec 2008
Duration 42 months
Evaluation summary (mar 2009) Total
12.5/15 S/T quality 4/5 Implementation
4/5 Impact 4.5/5

• Status 1st project in the reserve list
• April 2009 (unofficial communication) accepted
  for negotiation

2
Partnership

1. Consorzio CREO - LAquila, Italia (Coordinatore)
2. Fraunhofer Institute IPM - Friburgo, Germania
3. CNR IMM - Bologna, Italia
4. EADS Innovation Works - Monaco di Baviera,
   Germania
5. Elsag Datamat SpA - Italia
6. Universite de Lausanne - Losanna, Svizzera
7. University "Dunarea de Jos" - Galati, Romania
8. National Institute for Criminalistics and
   Criminology - Bruxelles, Belgio
9. National Bureau of Investigation - Helsinky,
   Finlandia
10. CNISM - Unità di Parma Parma, Italia

3
Project aim and concept

• Advanced sensor system to recognize and detect
  illicit drugs, illicit drug precursors and
  potential derivatives of key precursors
  (Amphetamine-type-stimulants - ATS)
• Innovative aspects
• Miniaturized Gas Chromatography (GC) as key
  chemical separation tool
• Hollow-Fiber-based Infra Red Absorption
  Spectroscopy (HF-IRAS) as key analytical tool

4
Sensor system
Sequence of operations and building blocks
5
Particle selective collection

• Molecules with amine groups have a high proton
  affinity

6
Preconcentration modules vapour-phase

• to treat analytes that can be vaporised without
  thermal decomposition
• free-base form amphetamines and precursors
• selective-trapping using quinoxaline cavitands
  (aromatic amines)
• flow-matching

7
Preconcentration modules liquid-phase

• detection of the ammonium salts of amphetamines
  (very low vapour pressure)
• selective trapping by phosphonate cavitands on Si

8
HF-IRAS module
9
GC module and detectors

• GC column and micro-fluidic circuitry
• MOX and Surface Ionization (SI) detectors

MOX array (IMM)
SI detector (EADS)
Example of MEMS based GC module
GC column (IMM)
10
WPs and partner roles
Work Package No Work package title Type of activiy Lead Participant No Lead Participant short name Person months Start month End month
0 Management MGT 1 CREO 18.25 M01 M42
1 Requirements RTD 8 NICC 28.50 M01 M06
2 Sensor System and Application RTD 1 CREO 69 M04 M42
3 Sampling module RTD 4 EADS 23 M01 M36
4 Treatment/pre-concentration module RTD 3 CNR IMM 47 M01 M36
5 HF-IRAS module RTD 2 FRAUNHOFER 68 M01 M36
6 GC module and detectors RTD 4 CNR IMM 37 M01 M36
7 Expert System RTD 7 UDJG 50.50 M01 M42
8 Experimental tests and performance assessment RTD 6 UNIL 63.50 M06 M42
9 Exploitation and dissemination of results OTHER 5 CREO 21.50 M01 M42
TOTAL TOTAL TOTAL 426.25
11
Project costs and EC contribution
Organisation short name TOTAL Grant requested
CREO 758,120.00 588,582.00 19.70
FRAUNHOFER 600,000.00 452,850.00 15.16
CNR IMM 454,000.00 342,750.00 11.47
EADS 660,000.00 349,500.00 11.70
ED 408,000.00 210,000.00 7.03
UNIL 432,000.00 324,000.00 10.84
UDJG 351,700.00 267,700.00 8.96
NICC 225,750.00 174,510.00 5-84
NBI 146,850.00 111,825.00 3.74
INSTM 220,000.00 186,000.00 5-56
TOTAL 4.256.420,00 2,987,717.00 100.00
12
Related research projects (Previous and
ongoing) EC FP4 SMOG EC FP5 Clean-Air EC FP6
GoodFood FISR RBNE019TMF FIRB Microsistemi per
applicazioni ambientali ed agroalimentari
NetLab ENVIREN NetLab PROMINER PRRIITT
UNITEC Progetto Pollution
Staff Ivan Elmi Stefano Zampolli
Gian Carlo Cardinali Enrico Cozzani
Fulvio Mancarella Piera Maccagnani
Alberto Roncaglia Maurizio Severi
Luca Masini Antonio Zani Fabrizio Tamarri Michele
Sanmartin Paolo Negrini Giulio Pizzochero