Peptic Ulcer Disease

1
Peptic Ulcer Disease
2
intro

• Acid
• Pepsin
• H. Pylori
• 30-40 of population affected
• gt 90 of duodenal ulcers
• 70 of gastric ulcers

3
Clinical features

• Burning epigastric pain
• Nausea
• Vomiting
• GI bleeding

4
diagnosis

• History and physical help
• Endoscopy required for diagnosis
• Numerous H. pylori tests
• Endoscopy
• Culture
• Urea breath test
• Stool antigen

5
treatment

• PPIs
• H2 blockers
• Sucralfate
• Antacids

6
complications

• Hemorrhage
• Perforation
• Obstructions

7
references

• Tintinalli, Ch. 81