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Rheumatoid arthritis

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Rheumatoid arthritis Tena Trbojevi Mentor: A. mega Horvat Rheumatoid arthritis chronic diesease inflammatory disease (inflammation of joint lining ... – PowerPoint PPT presentation

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Title: Rheumatoid arthritis


1
Rheumatoid arthritis
  • Tena Trbojevic
  • Mentor A. Žmegac
    Horvat

2
Rheumatoid arthritis
  • chronic diesease
  • inflammatory disease
  • (inflammation of joint lining)
  • autoimmune disease
  • (immune reaction against joint tissues -
    synovial membrane)

3
Rheumatoid arthritis
  • causes pain, swelling, stiffness, loss of
    function in the joints
  • generally occurs in a symmetrical pattern
  • may also attack tissue in the skin, lungs, eyes,
    and blood vessels

4
Rheumatoid arthritis
  • small joints of hands and feet affected first,
    larger joints later

5
Rheumatoid arthritis
  • begins during the most productive years (30 60)
  • occurs much more frequently in women than in men
    (wm31)

6
Rheumatoid arthritis
  • specific agent or agents are not yet known
  • infectious agents, such as viruses and bacteria,
    may trigger RA in people with an inherited
    tendency to develop the disease

7
Rheumatoid arthritis
  • synovitis
  • fibrous ankylosis
  • bony ankylosis
  • osteoporosis

8
Rheumatoid arthritis
9
Rheumatoid arthritis - symptoms
  • Around the joints
  • warmth
  • redness
  • swelling
  • pain
  • limitations in joint motion
  • General
  • sickness
  • tiredness
  • fever

10
Rheumatoid arthritis
  • can be difficult to diagnose in its early stages
  • Patient history
  • - questions about the intensity of pain
    symptoms
  • - frequency of symptoms
  • - what makes the pain better or worse
  • RTG, MRI, arthrography, arthroscopy
  • Blood test (RF, CRP, SE)
  • RF? Waaler- Rose test
  • 132normal
  • 164 pathological

11
Rheumatoid arthritis
  • Treatments can
  • relieve pain
  • reduce swelling
  • slow down or help prevent joint damage
  • increase ability to function
  • improve sense of well-being

12
Rheumatoid arthritis treatment
options
  • exercise
  • medication
  • stress reduction
  • DMARDs (disease-modifying anti-rheumatic drugs)
    methotrexate, leflunomide, sulfasalazine,
    cyclosporine
  • corticosteroids cortisone, hydrocortisone,
    prednisone
  • in some cases - surgery (joint replacement and
    tendon reconstruction - two types of surgery
    available to patients with severe joint damage )

13
Rheumatoid arthritis
  • research efforts focused on developing drugs
    that can reduce inflammation and slow or stop the
    disease with few side effects investigators
    trying to identify the infectious agents and
    understand how they work ? new therapies
  • scientists are also examining why rheumatoid
    arthritis often improves during pregnancy

14
Rheumatoid arthritis
  • http//www.medicinenet.com/rheumatoid_arthritis_pi
    ctures_slideshow/article.htm
  • http//video.about.com/arthritis/Chronic-Rheumatis
    m-Hand.htm
  • http//nihseniorhealth.gov/videolist.htmlrheumato
    idarthritis

15
  • References
  • http//nihseniorhealth.gov/videolist.htmlr
    heumatoidarthritis
  • http//www.medicinenet.com/rheumatoid_arthriti
    s_pictures_slideshow/article.htm
  • http//video.about.com/arthritis/Chronic-Rheum
    atism-Hand.htm
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