PowerPoint-presentatie

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IMPLEMENTATION OF THE THREE Rs
The role of education and training
L.F.M. van Zutphen
Utrecht
University
The Netherlands
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The successful implementation of the Three Rs
heavily depends upon education and training
of persons involved in animal experimentation.


Balls, M., Goldberg, A., Fentem, J. et al.
The
Three Rs The way forward
ATLA 23(6), 838-866, 1995
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EDUCATION
Development of proper attitude
TRAINING
Acquisition of practical knowledge and skills
needed for the design and conduct of animal
experiments or for the replacement, reduction,
refinement alternatives.
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LEGISLATION
Council Directive 86/609
Art.7.1 Experiments shall be performed solely by
competent authorized persons, or under the direct
responsibility of such a person
Art. 14 Person who carry out experiments or take
part in them shall have appropriate
education and training
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DEFINING COMPETENCE
Council of Europe (1994) Resolution on education
and training of persons working with laboratory
animals
FELASA (1995) Recommendations on education and
training of persons working with laboratory
animals
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EDUCATION AND TRAINING IN LAS

• Required for
• Persons taking care of animals (Cat. A, animal
  caretaker)
• Persons carrying out experiments (Cat. B, animal
  technician)
• Persons responsible for design of experiments
  (Cat. C, scientist)
• Persons specialised in LAS at post-graduate
  level (Cat. D, animal welfare officer)

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COMPETENCE SCIENTIST (CoE / FELASA)

• Graduate study (MSc) biomedical discipline
• (e.g. biology medicine veterinary
  medicine pharmacy)

• Course on laboratory animal science (80 hours)

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• COURSE LABORATORY ANIMAL SCIENCE
• Biology and husbandry of laboratory animals
• Genetic standardisation and quality control
• Gnotobiology and disease control
• Animal models and experimental design
• Experimental procedures
• Anaesthesiology and analgesia
• Animal alternatives
• Ethics and animal welfare
• Emphasis on competence and attitude

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REQUIREMENTS FOR CAT. C (SCIENTIST) IN
EU-COUNTRIES
Graduate study (MSc) in a biomedical discipline
Required by law
Not required by law
Austria Belgium Finland France
Germany Greece Italy Netherlands Sweden
Denmark Ireland Luxembourg
Portugal Spain United Kingdom
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REQUIREMENTS FOR CAT.C (SCIENTIST) IN EU-COUNTRIES
Course on Laboratory Animal Science
Required by law
Not required by law
Denmark (80 h) Finland (40 h) France (80
h) Netherlands (120 h) Sweden (80 h) United
Kingdom (80 h)
Austria Italy Belgium
Luxembourg Germany Portugal
Greece Spain Ireland
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NEED FOR HARMONISATION
OPORTUNITY
REVISION OF COUNCIL DIRECTIVE 86/609 (2002-2003)
PRIORITY
REQUIREMENTS COMPETENCE OF SCIENTISTS
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EUROPEAN SCIENCE FOUNDATION (ESF)
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RI
Finl. Akademi
Royal Society MRC
Eight organisations
DNV/NF
DFG
R I A
PAN
KNAW / NWO
ACR
OAW
FNRS
MTA
CNRS / INSRM
ACL / ICCTI
CSIC
SNFWA
EIE
CNR
TBTAK
EUROPEAN SCIENCE FOUNDATION
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Intrinsic value recognised
Three Rs strongly endorsed
Support for animal welfare research
ESF Position Paper Animal Use in Research
Ethics policy editorial boards journals
Review protocols animal ethics committees
Education and training
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ESF STATEMENT ON EDUCATION
Investigators and other personnel involved in the
design and performance of animal-based
experiments should be adequately educated and
trained. ESF Member Organisations should
encourage the development and organisation of
accredited courses on laboratory animal science,
including information on animal alternatives,
welfare and ethics.
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COURSE LABORATORY ANIMAL SCIENCE (The Netherlands)

• Length of course is three weeks

• Started in 1986

• Maximum number of participants is 20

• Presently organized at 7 universities

• Centrally coordinated Utrecht University

• More than 5000 students have successfully
  finished
• 
  the course

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Russell and BurchThe Principles of Humane
Experimental Technique, 1959

• Replacement
• Reduction
• Refinement

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Im so proud! All of my kids are going into
research