Focus on Immune Function

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Focus on Immune Function
Km
Matol Glucosamine
Biomune OSF Plus

• EnzyDigest

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Immune System

• How are the powers of the immune system being
  harnessed to treat diseases?
• The immune system has a remarkable ability to
  defend itself - but scientists have realized
  immunotherapy can increase natural defenses

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Km is immunotherapeutic

• Immunotherapy - internal or external strategies
  to boost immune response
• 14 unique botanicals contribute over 100 specific
  antioxidant rich plant chemicals
• Natural biological substances
• Antioxidants in Km increase bodies natural
  defenses

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Supporting Cellular Structure

• Plant chemicals from herbs in Km keep cellular
  membranes sturdy and injury free
• As antioxidants, Km plant chemicals, resist free
  radical damage from every day living
• Are they better than simply eating fruits and
  vegetables or chewing licorice root?

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From the USDA Human Nutrition Research Center on
Aging at Tufts University

• Liquid plant extracts were MORE effective in
  elevating blood plasma antioxidant levels than
  solid foods
• In the study, regular meals containing fruits and
  vegetables elevated antioxidant levels in the
  blood by 10
• Liquid strawberry and spinach extract, equivalent
  to 8-10 oz of produce, boosted antioxidant levels
  an additional 20

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The Immune System is complicated

• We need to protect our own systems
• 1. Food eaten and the nutrients in those foods
  act protectively
• 2. Sleep matters - it is protective and
  restorative
• 3. Stress matters - it negatively influences
  immune function
• 4. Exercise matters - it is protective and
  counters stress
• 5. Km Supplementation

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Km Acts Like A
Protective Preventive Proactive
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Km Prevents and Protects

• Specific Plant Chemicals or Antioxidants -
  different from vitamins and minerals
• To fight oxygen
• producing free
• radicals

• Minerals
• To support blood building and nerve transmission
• Potassium
• Iron

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Km balances cellular pH

• Our body water and blood is balanced with acid
  and alkaline substances
• Food, beverages, stress, disease, medication can
  alter pH balance
• Balanced pH of 7 indicates optimal health
• Km regulates pH balance through oxygenation of
  blood

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Examples of everyday substances that alter pH
levels

• Low pH more acid vs. High pH more alkaline
• Coffee - lowers pH
• Baking soda - raises pH
• Lemon and tomato juice - lowers pH
• Household ammonia or oven cleaner - have high pH
  values

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Enzymes and pH levels

• Body processes can work only under delicately
  balanced conditions when the pH level is just
  right
• An enzyme that works at one pH level will be
  deactivated at a pH level other than this perfect
  level
• Km (plant chemicals) are buffers to regulate the
  delicate pH balance

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Km regulates bodys internal environment

• Cant feel it
• Cant see it
• Maintains the balance between highs and lows of
  acid and alkaline substances

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Immune Booster Biomune OSF Plus

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Bacterial Resistant Drugs Force us to Focus on
Nutrition

• Dietary Supplements improve immune function
• Herbal therapies rich in antioxidants boost cell
  membrane integrity resisting bacterial or viral
  invasion
• Plant chemicals NOT FOUND in food can act as
  immune modulators to stimulate natural killer
  cell activity to fight foreign microbes

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Astragalus - another protective substance

• Active ingredients in Astragalus
• Choline - protective of nerve endings
• Bioflavinoids - antioxidant properties
• Astragalan B - a complex carbohydrate shown to
  protect the body from toxins that control
  bacterial infections

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Astragalus Increases Interferon Production

• Interferons act on immune system by stimulating
  both T cells and macrophages
• T cells are a type of white blood cell that binds
  to the macrophages and together produce chemical
  substances called interleukins to help protect us

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Biomune OSF Plus An Obvious Choice

• Active ingredients
• Whey extracts
• Astragalus
• Whey originates from cows milk but is an extract
  therefore no dairy fats remain
• Whey contains nano-molecular info-tides
  that support and normalizes immune activity

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Matol GlucosamineLiquid Formulawith MSM,
Collagen Hydrolysate and Devils Claw

• For Joint Health

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Joint Disease A Significant Problem

• 20.7 million Americans have osteoarthritis (OA)
  making it the most common musculoskeletal
  condition
• OA is the 4th most frequently predicted cause of
  health problems in women and 8th in men worldwide
• 70 million Americans suffer from chronic pain
  associated with bone joint conditions

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Osteoarthritis

• Millions of people worldwide are afflicted with
  the disabling joint pain of osteoarthritis
• As joints become swollen and painful, physical
  activity decreases
• Decreased physical activity reduces joint
  flexibility and more discomfort
• Decreased physical activity leads to overweight
  and obesity
• Overweight and obesity put additional stress on
  painful joints

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A Unique Building Material
Cartilage

• 5 specialized cartilage cells (chondrocytes)
• 95 water extracellular matrix

• No blood, lymph vessels
• No nerve fibers

Type II Collagen Proteoglycans
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Evolution of Joint Pain
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Factors Affecting Joint Health
Physical activity
Weight
Dietary habits
Aging
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Obesity Increases Risk

• Overweight people display OA by age 40
• Some physicians have identified overweight 20-30
  year olds with asymptomatic changes in joints
• Most typical sites of OA
• Hips
• Lower spine
• Knees
• Joints that fulfill a weight-bearing function
• Obesity is a risk factor for OA of the knee

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Osteoarthritis Most Common Joint Disease

• Risk factors
• Heredity runs in the family
• Gender occurs twice as often in women vs men
• Age risk increases with age
• Obesity and overweight
• Injuries from overuse or poor use of joints
• Post-traumatic change following surgery, fracture
  or injury
• Inflammatory joint disease
• Congenital deformity
• Immobility or physical inactivity

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There Is No Cure for OA

• Most frequent symptom of OA is pain upon movement
  with excess weight as a joint stressor
• Current treatments focus on reducing pain and
  inflammation
• Goals
• Keep patient mobile
• Avoid unnecessary stress to painful joint area
• Treatment is typically non-steroidal
  anti-inflammatory drugs (NSAIDs) to reduce joint
  pain, stiffness, swelling

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NSAIDs and Analgesics

• Suppress inflammation but do not improve the
  natural history of the disease
• Side effects
• Epigastric discomfort
• Gastric or duodenal ulcers
• Gastro-intestinal bleeding
• Exacerbate degenerative process of OA by
  decreasing production of glycosaminoglycan (GAG)
  synthesis
• Brandt, K. Should nonsteroidal anti-inflammatory
  drugs be used to treat osteoarthritis? Rheum Dis
  Clin N Am, 19931929-44.

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Preventing Osteoarthritis

• There are no medical cures for osteoarthritis
• The goal is to prevent it
• Maintain ideal body weight
• Eat proper amounts of vitamins and minerals that
  support optimal bone and joint health (calcium,
  magnesium, vitamin C and D)
• Take supplements that can help repair cartilage
  damage

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Glucosamine What is it?

• Natural compound found in healthy cartilage not
  found in foods
• Studies show glucosamine, taken regularly for 4-6
  weeks can reduce the joint discomfort of
  osteoarthritis

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Glucosamine

• An amino-monosaccharide (protein and
  carbohydrate)
• Derived from chitin in crustacean shells
• May stimulate the formation of proteoglycans
• May have anti-inflammatory activity
• No known toxicity at doses far exceeding those
  used in human clinical trials

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Glucosamine is safe and natural

• Many products used to reduce discomfort caused by
  osteoarthritis are non-steroidal
  anti-inflammatory medicines
• Over time and with consistent use these products
  can damage stomach lining
• Glucosamine has no negative side effects and is
  safe for people of all ages to take

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Methyl Sulfonyl Methane (MSM)

• 500 mg Methyl Sulfonyl Methane (MSM)
• Derived from plants, MSM supports healthy
  connective tissues like tendons, ligaments, and
  muscle
• Sulfur found in MSM helps form essential amino
  acids methionine and cysteine involved in
  reconstruction of cartilage
• Sulfur levels are low in people with
  Osteoarthritis

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MSM Methyl-sulfonyl-methane

• OA patients have lower than normal levels of
  serum and synovial sulfur
• Sulfur stimulates proteoglycan synthesis and
  promotes cartilage formation
• Studies
• claim to reduce pain, stiffness, and swelling
  along with increasing flexibility and circulation

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Additional ingredients

• 150 mg of Devils Claw
• As an herb, used to reduce low back and neck pain
  due to its anti-inflammatory properties

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Additional ingredients

• 100 mg Collagen hydrolysate
• Collagen hydrolysate is an exciting ingredient
  that has been shown by itself to reduce
  discomfort caused by osteoarthritis
• Studies have shown that regular use can improve
  joint strength in the knee
• Collagen is the fibrous substance found in skin,
  cartilage, bone, and other tissues
• Collagen hydrolysate glucosamine have been
  found to regenerate cartilage in joints

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Collagen Hydrolysate

• Derived from fish
• A pure protein
• FDA granted status Generally Recognized as Safe
  (GRAS) as a dietary supplement (same as sugar and
  salt)
• 10 g/day results in optimal cartilage
  regeneration
• Studies by Oesser, et al, demonstrated
  preferential uptake of intact peptide in joint
  cartilage
• Collagen hydrolysate appears to stimulate type II
  collagen synthesis
• Oesser, S, et al. J. of Nutrition, 129189-195,
  1999.
• Moskowitz, RW. Seminars in Arthritis and
  Rheumatism, 3087-99, 2000.
• Oesser, S, et al. Cell Tissue Research,
  311393-399, 2003

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Collagen HydrolysateStimulates Collagen Synthesis
CH significantly increases type II collagen
synthesis in chondrocyte cell culture
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Matol Glucosamine Liquid Formula

• Large pills or capsules of glucosamine are
  traditional delivery routes
• Swallowing is difficult
• Matols new liquid formula makes taking this
  daily joint health supplement easy to use

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A Wise Decision

• Good nutrition involves selecting foods that
  contain rich sources of vitamins, minerals,
  proteins, carbohydrates and fats
• Good nutrition involves eating the correct amount
  of calories to achieve and maintain ideal body
  weight
• No amount of appropriate foods can offer you
  glucosamine, MSM, devils claw, and collagen
  hydrolysate - it has to be a supplement

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EnzyDigest

• Natural enzymes to aid digestion of food
• Alpha-amylase - digests starchy carbohydrates
• Proteases - digests proteins
• Bromelain - digests proteins
• Lipase
• Lactase

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Enzymes Made in the Body are Easily Destroyed

• When food is eaten, enzymes are naturally
  secreted by a variety of organs to break the food
  into tiny particles
• Types of foods or beverages consumed alters pH of
  body water and blood
• pH levels can destroy enzyme action
• Food poorly digested, causing GI upset

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Enzymes Helper Hatchets

• By taking EnzyDigest you assure yourself of
  adequate digestive enzymes to break food down
  appropriately
• Improved digestion decreased physical stress on
  the body