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Endometriosis

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Title: Endometriosis


1
Endometriosis
  • Christina Hodder
  • Leanne Jesso

2
Introduction
  • Uterine lining implants itself to other organs in
    the pelvic region. Ex.. Ovaries, bladder,
    fallopian tubes
  • Appears as cysts and adhesions
  • Causes a great deal of menstrual pain
  • Affects women of the reproductive age
  • Remains a hidden disease until other problems
    arise

3
Brief History
  • Thought to be a disease of the upper class, white
    woman
  • The first report in 1860 by a Dr. Rokitansky

4
Symptoms
  • Pelvic Pain (acute or chronic)
  • Dyspareunia (painful intercourse)
  • Painful bowel movements
  • Premenstrual staining and abnormal bleeding
  • Difficult urination and/or blood present in the
    urine
  • Infertility

5
Some Theoretical Causes
  • Genetic, runs in the family
  • Retrograde menstruation
  • Problems in the immune system
  • Estrogen (natural and synthetic)

6
Effects on the Body
  • Linked to infertility
  • Miscarriages
  • Loss of reproductive organs (hysterectomy)
  • Psychologically damaging
  • Chronic pain

7
Methods of Diagnosis
  • Most cases diagnosed because of other
    complication(s)
  • Laparoscopy is best detector and treatment option

8
Some Classifications
  • Mild- Rare, scattered lesions, no scarring
  • Moderate- Minimal adhesions and superficial
    implants
  • Severe- Reproductive organs are bound down by
    growths, bladder and/or bowel may also become
    affected

9
Stages
10
Treatment Options- Surgical
  • Laparoscopy- method of choice
  • Conservative surgery
  • Hysterectomy

11
Patient Satisfaction
12
Treatment Options- Non surgical
  • Gonadotropin-releasing hormone agonists, Danazol,
    Norethindrone, Gestrinone
  • All acyclic, some high androgen, others high
    progesterone, all low estrogen
  • Negative side effects such as accelerated bone
    loss, weight gain, nausea, breakthrough bleeding
  • Pain killers (aspirin, morphine, and codeine)

13
Patient Satisfaction
14
Statistics
  • 6-58 of infertile women have endometriosis
  • 30-50 of women with endometriosis are infertile
    (twice the rate of the general population)
  • Up to 22 of women have no symptoms
  • 30-50 of women with this disease have had
    miscarriages
  • Between 1965-1984 2 million US women between
    ages 25-54 diagnosed received a hysterectomy
  • Painful disease 66 of women experience chronic
    pain
  • 1 out of 10 women from menarche to menopause can
    be expected to have some degree of endometriosis
    EXCEPT women with a sister, mother, or daughter
    already diagnosed, then incidences double to 1
    out of 5

15
Interesting Facts
  • Men can also develop endometriosis after
    prolonged treatments involving synthetic estrogen
  • Reported cases in primates such as baboons,
    African Green Monkeys, and Rhesus Monkeys
  • Pharmaceutical companies cashing in on womens
    pain 3 month Endometriosis Kit 525.95 USD
  • Endometriosis has been removed from areas other
    than the abdomen such as the thigh, thumb, and
    knee

16
Photos
  • A small adhesion on an ovary about to be removed
    surgically

17
Photos
  • Endometriosis growing on the ovary and fallopian
    tube

18
Photos
  • Severe endometriosis on the back of the uterus
    causing adhesions of the bowel and pelvic organs

19
Conclusion
  • No cure
  • Disease of coping
  • Combination therapy involving surgery, hormones,
    and (if needed) assisted reproduction

20
Works Cited
  • Buttram, Veasy C. Jr. et al. Endometriosis
    Advanced Management and Surgical Techniques. New
    York Springer-Verlag, 1995.
  • OConnor, Daniel T. Endometriosis. London
    Churchill Livingstone, 1987.
  • Shaw, Robert W. Endometriosis Current
    Understanding and Management. London Blackwell
    Science Ltd., 1995.
  • Wilson, Emery A. Endometriosis. New York Alan R.
    Liss, 1987.
  • http//www.endometriosis.org/
  • http//ladytobaby.com/show.php?cat38item164
  • www.dictionary.com

21
Websites
  • http//ladytobaby.com/show.php?cat38item164
  • http//www.endo.org.uk/painsurveytoplinepreliminar
    yresults05.doc
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