ENG Advisory Committee May 11, 2005

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ENG Advisory Committee May 11, 2005

• BES
• OVERVIEW
• Bruce Hamilton
• Acting Division Director

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BESStructure Funding Profile

• Three (3) Clusters
• Biochemical Engineering/Biotechnology (BEB)
• Biomedical Engineering/Research to Aid Persons
  with Disabilities (BME/RAPD)
• Environmental Engineering and Technology (EET)
• Each cluster is funded at about 1/3 of BESs
  overall budget ( 50 million/year)

3
BES Team

• Program Officers
• Pat Brezonik Gil Devey (PT) Fred Heineken
• Lenore Clesceri (PT) Cindy Ekstein Marshall
  Lih
• Semahat Demir Leon Esterowitz Tom Waite
• Mike Domach (PT) Bruce Hamilton (ADD) Bill
  Weigand (PT)
• Support Staff
• Toni Baker LaWanda Prailow Sherri Swann
• Eula Patterson Marcia Rawlings LaTanya Darby
• Sunny Phelps Joyce Simpson

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BES Draft VisionAn Aspiration for the Future...

• BES is an important and significant
• Catalytic Driver for the role of
• Biology and the Environment
• in advancing the
• Frontiers of Engineering
• research, innovation, and education.

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Why the Role of BES Is As a Catalytic Driver
1. Resources needed. 2. At NSF, the involvement
of Engineering with Biology and the Environment
has become pervasive,going way beyond BES.
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Biology All 6 NSF ENG DivisionsSupport
Biology-Oriented Awards

• BES All aspects of biology and engineering

CMS Biomechanical Eng (e.g., bone biomaterials)
CTS Biotransport Eng (e.g., blood flow fluid
dynamics)
DMII Engineering Health Care Delivery
ECS Many aspects of biology and engineering
(e.g., biomedical imaging)
EEC Centers, Dept. Reform (biology and
engineering)
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CISE Directorate AlsoSupports
Engineering/Biology-Oriented Awards

• Example--
• ITR 0205741 Simulation-Based Medical Planning
  for Cardiovascular Disease
• PI Charles Taylor
• Department of Bioengineering
• Stanford University
• 3.7 million over 5 years

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EHR Directorate AlsoSupports Engineering/Biology-
Oriented Awards

• Example (undergraduate course)
• NSF 0231313
• Development of Educational Materials that
  Strengthen Students Problem-Solving Skills for a
  Bioengineering Fundamentals Course
• PI Ann Saterbak
• Rice University
• 75K over 2 years

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And for the case of the Environment

• Just as for the pervasiveness of Biology in
  Engineering,
• so also for the pervasiveness of the Environment
  in Engineering.
• (goes way beyond BES, therefore the role of BES
  as Catalytic Driver is appropriate)

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BES Draft Mission

• Research and Innovation Enable and facilitate
  the deployment of new innovations in BESs fields
  in service to society for use in the medical,
  biotechnology, and environmental arenas
• Education Advance bioengineering and
  environmental engineering through the development
  of creative programs by new and diverse faculty
  (example Emphasis on CAREER awards, including
  under-represented group PECASE awardees)

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BES Strategies

• To pursue our Vision and Mission,
• BES has evolved
• 7 Key Strategies
• (Time to cover only 4)

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BES Strategy 1

• Develop and support
• the best and the brightest researchers,
  innovators, educators
• in BESs fields,
• with one emphasis being on
• new faculty

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BES Strategy 1 Develop and support the best and
the brightest researchers, innovators,
educators in BESs fields, with one emphasis on
new faculty.

• Examples
• 2004 Waterman Award Winner Kristi Anseth (1998
  BES CAREER awardee).
• 1999 Waterman Award Winner Chaitan Khosla (1994
  NSF Young Investigator awardee from BES).
• 2004 IOM Inductees Cato Laurencin (BES PI from
  early in career) and Frances Arnold (1989 BES
  PYI also NAE in 2000).
• 2002 HHMI 1 Million Undergraduate Educator Award
  Winner Rebecca Richards-Kortum (1991 BES PYI).
• 2002 NAE Draper Award and 1998 Lemelson Invention
  Prize Winner Bob Langer (long-time BES PI,
  starting early in his career).
• 2002 NAE Inductee (Industrial Ecology) Tom
  Graedel (BES is principal source of support,
  starting early in his academic career)
• 2005 NAE Inductees George Georgiou (1987 BES
  PYI) and Harvey Blanch (long-time BES PI).
• Future Goal Develop and support more winners!

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BES Strategy 2

• Aggressively pursue and implement
• partnerships with other ENG divisions,
  directorates, and agencies, even if tolerance of
  high risk is required
• (e.g., solicitation risk)

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BES Strategy 2 Aggressively pursue and
implement partnerships with other ENG divisions,
directorates, and agencies.

• Examples
• Metabolic Engineering NSF, NIH, DOE, EPA, NASA,
  NIST, DOD, USDA
• MATES NSF, NIH, NIST, DOD, FDA, DOE, NASA
• QSB ENG (5 divisions), BIO, MPS, CISE.
• Biophotonics NSF, NIH, DARPA.
• Multiscale Bio Modeling NSF, NIH, NASA, DOE.
• CRCNS ENG (BES, ECS), CISE, BIO, SBE, NIH.
• MUSES ENG (5 divisions), SBE, CISE, MPS
• IGI ENG (BES, ECS), CISE, NIH, NASA
• Forum on the Interface of the Life Sciences and
  Physical Sciences NSF, NIH, NASA, NIST, DOE,
  USDA, EPA, DOD, FDA, NOAA
• Future Goal
• Additional innovative partnerships with
  high-return leverage.

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BES Strategy 3

• Dynamically interact,
• through extensive outreach, with
• universities, industry, foundations,
  non-profits, other agencies, and professional
  societies and topical meetings.

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BES Strategy 3 Dynamically interact, through
extensive outreach, with universities, industry,
foundations, non-profits, other agencies, and
professional societies and topical meetings.

• Examples
• Universities Workshops (e.g., for CLEANER, at
  Stanford, U. of Minn., Duke, U. of Iowa, RPI)
• Industry BES Biochemical Engineering Workshop
  (Amgen, Biogen, Chiron, Genencor, Genetics
  Institute, engeneOS Biosystems, Inc.) and 2005
  Metabolic Engineering Conference with industry.
• Foundations Whitaker, HHMI.
• Non-profits MdBio, Inc., the National
  Academies.
• Professional Societies AIChE, ACS, IEEE, BMES,
  AIMBE, AEESP, WEF, ASEE, SWE, WEPAN and others.
• Future Goal Strengthen outreach, with
  high-return (intellectual, financial, diversity).

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BES Strategy 4

• Create and implement
• Big Ideas.

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BES Strategy 4 Create and implement Big
Ideas.

• Examples
• - CLEANER
• - Engineering Systems Biology
• - Biophotonics (BP) / IGI
• Future Goals
• - Implement CLEANER, include other agencies.
• - Extend QSB and include other agencies.
• - Grow BP / IGI partnership with other
  agencies.

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BES Draft VisionAn Aspiration for the Future...

• BES is an important and significant
• Catalytic Driver for the role of
• Biology and the Environment
• in advancing the
• Frontiers of Engineering
• research, innovation, and education.