Ch18 Pattern Formation

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• Ch18 Pattern Formation Regeneration
• Types of Regeneration
• Stem Cells (undifferentiated)
• Morphallaxis
• Epimorphosis
• Compensatory Regeneration (differentiated)

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Pattern Formation Regeneration Epimorphosis
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• Regeneration
• Epimorphosis
• Limb regeneration - Blastema
• What is necessary for limb regeneration?
• Denerve then amputated ? ?
• Amputation ? add NGF ? ?
• Nerve transplants in animals which normally lack
  regeneration
• Newborn Opposum
• 1. Hindlimb Amputation ? ?
• Supplemental nerve tissue ? ?

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Epimorphosis
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Hydra freshwater cnidarian Morphallaxis
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Hydra regeneration gradients Head Activator
vs. Head Inhibitor both from Hypostome Budding -
level of HA at gastric bud Role of nerves
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Compensatory Regeneration