Chapter 26(partial) Sterol Metabolism and Coronary Artery Disease

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Chapter 26(partial)Sterol Metabolism and
Coronary Artery Disease
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Big Picture Endogenous and Exogenous Cholesterol
Metabolism
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Cholesterol Synthesis
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CAD-Risk Factors

• High LDL
• Smoking
• Type I and II diabetes
• High Blood pressure

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Coronary Artery Disease
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Coronary Artery Disease-Treatments

• Statins-
• HMG CoA reductase inhib.

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Coronary Artery Disease-Treatments

• Fiber/Cholestyramine/etc.

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Coronary Artery Disease-Treatments

• Niacin
• Antiinflammatories
• Blood Pressure
• DIET!!! (sat/trans fats)