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Research Funding: Navigating the NIH Grant Maze


Research Funding: Navigating the NIH Grant Maze. Special thanks: Marianna Bledsoe, M.A. ... Regular Research Grant: R01. Program Project Grant: P01 ... – PowerPoint PPT presentation

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Title: Research Funding: Navigating the NIH Grant Maze

Research Funding Navigating the NIH Grant Maze
  • Special thanks
  • Marianna Bledsoe, M.A.
  • Resources Development Branch
  • Cancer Diagnosis Program,
  • National Cancer Institute

NIH Structure
  • 27 Institutes and Centers (ICs)
  • Institutes
  • e.g. National Cancer Institute, National Heart,
    Lung, and Blood Institute, National Institute of
    Dental and Craniofacial Research , National
    Institute of Neurological Disease and Stroke,
    National Institute of Biomedical Imaging and
  • Centers
  • e.g. Center for Scientific Review (CSR)
    National Center for Research Resources

Whos Who
  • Review Staff
  • Center for Scientific Review (CSR) or
    Institute/Center staff-these are the people who
    can answer general questions
  • Responsible for receipt, referral and review of
  • Program Staff
  • Responsible for the scientific funding and
    oversight of grants

What is NIH Looking For ?
  • The best science
  • Expertise and resources to get it done
  • Who Can Get One?
  • Any qualified scientist with academic credentials
    and experience appropriate to the application
  • Institution is the grantee (exceptions
    fellowships and career rewards)
  • Shared responsibilities
  • Domestic or Foreign

Updates on Budget 2003
  • Continuous resolution funding levels low
  • NCI
  • New Investigator RO1 17
  • Continued grant RO1 17
  • New initiatives RO1 12
  • 2003 Senate and House Approved Budget
  • 27.3 billion to NIH (16.2 increase over 2002)

Types of NIH Grants
  • Training Grants
  • Investigator-Initiated
  • Regular Research Grant R01
  • Program Project Grant P01
  • Specialized Programs of Research Excellence
  • Other
  • Small Business
  • Innovative Research Grant (SBIR)
  • R43, R44
  • Technology Transfer Research (STTR)
  • R41, R42

Keep up with NIH Initiatives
  • Initiatives
  • Used by Institutes and Centers to stimulate
    research in particular areas
  • Announced in NIH Guide
  • http//
  • Program Announcements
  • No set aside, Usually reviewed by CSR
  • Exploratory Grants R21
  • R21/R33

The Application Process
  • PHS 398 for most competing grants
  • Instructions critical-dont miss the deadline
  • Special requirements for animals, human subjects,
    inclusion of women, minorities, and children
  • Call appropriate NIH staff or research officers
    of University for help

…and more Process
  • Receipt and Assignment
  • Applications submitted to Center for Scientific
    Review-Study section organization in process of
    review and restructure
  • Assigned to an IC and an appropriate Scientific
    Review Group (SRG)
  • Initial Peer Review
  • Managed by Scientific Review Administrators (CSR
    or IC staff)
  • Generally 3 reviewers, make recommendation and
    discussed in section if viewed in upper half.
  • Some initiatives and grant types have special
    review process

Understand the system….
  • Scoring
  • Priority scores
  • Each SRG member assigns a score ranging from 1
  • 1 best 5 worst
  • Composite score calculated (100 best 500 worst)
  • Percentiles
  • Rank relative to other applications reviewed by
    SRG at the last three meetings
  • Range from .5 (best) to 99.5 (worst)

and the intent of Feedback
  • Summary Statement (the pink sheet)
  • Summarizes comments during review process
  • Provides an opportunity for revision based on
    reviewers comments-argue at your own risk!
  • will also include a summary of discussion of all
  • Advisory Council/Board Review
  • Second level of peer review
  • Review applications for human subjects, animal
    welfare concerns ensure that initial peer review
    is appropriate
  • Concurrence with initial peer review

IC Funding Decisions
  • Pay lines
  • Scientific Merit
  • Programmatic Balance
  • Budgetary Factors
  • Other considerations

You made it!
  • Pre-Award
  • IC staff review issues that must be resolved
    prior to funding
  • Human subjects/animal welfare issues
  • Inclusion of women, minorities and children
  • Scientific overlap
  • Award
  • Negotiation by grants management staff
  • Notice of Grant Award
  • Post-Award
  • Non-competing continuation (yearly progress

Dont Forget
  • Follow grant application instructions (PHS398 or
  • Identify yourself as a new investigator
  • If submitting in response to an initiative,
    address special requirements and specific points
    listed in the announcement-why is your
    application meritorious?
  • Pay careful attention to the review criteria
  • Develop clearly stated hypothesis
  • Neatness, spelling and presentation are very

Remember to
  • Write clearly and concisely KISS and FOCUS-your
    reviewer may not be an expert in your area
  • Document resources and institutional support
  • Demonstrate solid understanding of literature,
    strengths and weaknesses methods
  • Describe potential pitfalls and alternative
  • Bring in collaborators to fill gaps in expertise
    and resources (document with letters of support)

Helpful Hints
  • Include information essential to the review in
    the body of the application, not the appendix
  • Organize using outline format, numbers per the
    instructions. Highlight or ital key information
    so it is not missed.
  • Your CV is an opportunity to impress, dont
    forget to update it and show a track record of
    productivity or reasons why not.
  • Base the budget on the science justify and
    address overlap
  • Seek advice and have others read your final draft

Career Track Opportunities
Cancer Training Branch Website