LISINOPRIL PATHWAY

1
LISINOPRIL PATHWAY In Homo sapiens
Blood stream
Arterioles
Capillaries
Renin P00797
Decreased Concentration
Juxtaglomerular Apparatus
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2
Adrenal Cortex
ACTIVATION
Decreased Concentration
Nephron
ACTIVATION
DISTAL CONVOLUTED TUBULE/COLLECTING TUBULE
URINE


Increased Concentration
Increased Concentration
LUMEN
Amiloride-sensitive sodium channel
SCNN1A P37088
AQP2 P41181
SCNN1B P51168
SCNN1G P51170
SCNN1D P51172
Decreased Concentration
Decreased Concentration
Mineralocorticoid receptor P08235
ATP1A1 P05023
FXYD2 P54710
ATP1A2 P50993
ATP1B4 B7ZKV8
AQP3 Q92482
Na/K ATPase
ATP1A3 P13637
ATP1B3 P54709
ATP1A4 Q13733
ATP1B1 P05026
ATP1B2 P14415
INTERSTITIUM
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3
Systemic Arteries
Decreased Concentration
Voltage-gated T-type calcium channel (ICaT)
Voltage-gated L-type calcium channel (ICaL)
ATP-sensitive inward rectifier potassium channel
(IKATP)
CACNA1G O43497
CACNA1H O95180
CACNA1C Q13936
CACNA2D3 Q8IZS8
CACNB2 Q08289
KCNJ8 Q15842
KCNJ11 Q14654
ABCC8 Q09428
ABCC9 O60706
Endothelin B receptor P24530
Endothelin-1 receptor P25101
Vascular Smooth Muscle Cell
ACTIVATION
ACTIVATION
Type-1 angiotensin II receptor P30556
ACTIVATION
1-phosphatidylinositol- 4,5-bisphosphate
phosphodiesterase beta-1 Q9NQ66
ACTIVATION
Ca2
ATP HMDB00538
ADP HMDB01341
ACTIVATION
Beta-2 adrenergic receptor P07550
Alpha-1A adrenergic receptor P35348
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