The Visible Human Project

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The Visible Human Project

• "The Visible Human Project includes digitized
  photographic images for cryosectioning, digital
  images derived from computerized tomography and
  digital magnetic resonance images of cadavers."

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The Visible Human Project

• Find a normal male and female cadaver
• Fresh CT MR
• Fill blood vessels and cavities with contrast
  media
• Pose and stabilize in opaque gel
• Freeze the cadaver
• Cut cadaver into blocks
• Frozen CT
• Grind down block and take photograph

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Infuse blood vessels and fill cavities with
contrast media (resin)
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Cryo-section Data Collection
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Data Collection
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Data Collection
CT (bone)
MRI (proton-density)
MRI (T1)
MRI (T2)
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Data Collection
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Data Collection

• Photographic cross-sections
• Volume Dimensions 1760 x 1024 x 1878Pixel
  Dimensions .33 mm x .33 mm x 1 mmPixel Depth
  24-bit (8-bits x RGB)Volume Size 9.5 GB
• Computed Tomography (CT) - in fresh state
• Volume Dimensions 512 x 512 x 500Pixel
  Dimensions variable x variable x 1 mmPixel
  Depth 16-bitVolume Size 250 MB
• Computed Tomography (CT) in frozen state
• Volume Dimensions 512 x 512 x 1878Pixel
  Dimensions variable x variable x 1 mmPixel
  Depth 16-bitVolume Size 939 MB

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Data Collection

• Photographic cross-sections
• Volume Dimensions 1664 x 928 x 5189
• Pixel Dimensions .33 mm x .33 mm x .33 mm
• Pixel Depth 24-bit (8-bits x RGB)
• Volume Size 22.4 GB
• Computed Tomography (CT) - in fresh state
• Volume Dimensions 512 x 512 x 1730
• Pixel Dimensions variable x variable x 1 mm
• Pixel Depth 16-bit
• Volume Size 864 MB

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The Visible Human
Transverse Coronal Sagittal
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Segmentation and Classification
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Semi-automatic Segmentation
Mostly done by anatomists using a drawing and
filtering program.
Spline interpolation of surface

• Marr-Hildreth edge detection filter, seed
  filling and neighbor connectivity filter

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Segmentation
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Classification
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Classification
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Classification