TRWG Report Implementation

1
TRWG Report Implementation

There is science and the application of science,
and these two are linked as the fruit is to the
tree Louis Pasteur, 1822-1895

• Lynn M. Matrisian, Ph.D.
• February 6, 2008

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TRWG Report Transforming translation -
harnessing discovery research for patient and
public benefit
Accepted by the NCAB June, 2007
IMPLEMENTATION TIMELINE
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A1 Flexible, Integrated Organizational Approach
Clinical Trials Advisory Committee
Advisory
NCI Director
Direct Report
Chair
Support
Translational Research Operations Committee
Coordinating Center for Clinical
Trials Translational Research Support Office
Support
Advisory
Oversight
Translational Research Prioritization Working
Group
Support
Extramural group
Intramural group
New entity
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A1 Flexible, Integrated Organizational Approach
Clinical Trials Advisory Committee
Advisory
NCI Director
Clinical Translational Advisory Committee
Direct Report
Chair
Support
Translational Research Operations Committee
Coordinating Center for Clinical
Trials Translational Research Support Office
Support
Advisory
Clinical and Translational Research Operations
Committee
Coordinating Center for Clinical
Trials Translational Research Support Office
Oversight
Translational Research Prioritization Working
Group
Support
Extramural group
Intramural group
New entity
5
Expansion of CTWG-created Advisory Committee

• Clinical Trials Advisory Committee becomes
  Clinical and Translational Advisory Committee
  (CTAC to CTAC)
• Efficient piggy-backing on existing structure
• Value in having a single body oversee entire
  spectrum of early and late translational research
• Implementation
• Charter change to incorporate Translational
  Research
• Additional members with translational research
  expertise

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NCI Internal Organizational Changes

• Clinical Trials Operating Committee becomes
  Clinical and Translational Research Operating
  Committee (CTOC to CTROC)
• Additional representation from the Division of
  Cancer Biology
• Additional representation from the Office of
  Technology Transfer
• Agenda to focus on CTWG once/month, TRWG
  once/month
• Coordinating Center for Clinical Trials (CCCT)
  expands to incorporate mission of the
  Translational Research Support Office (TRSO).
• Lynn Matrisian (50 IPA)
• Additional staff

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Action Items

• Modify CTAC Charter to reflect expansion of
  responsibilities
• Add members to the CTAC to provide additional
  translational research expertise
• Expand Coordinating Center for Clinical Trials to
  incorporate Translational Research Support Office
  functions

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TRWG Report Transforming translation -
harnessing discovery research for patient and
public benefit
Initial discussions with CTAC Working Group, Feb
4 2008
IMPLEMENTATION TIMELINE