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DNA polymerase Families, Error rates and Functions

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DNA polymerase Families, Error rates and Functions ... as 1) pyrimidine dimer, 2) polycyclic aromatic DNA adducts and 3) abasic sites. ... – PowerPoint PPT presentation

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Title: DNA polymerase Families, Error rates and Functions


1
DNA polymerase Families, Error rates and
Functions
A, B, C and X families of DNA polymerases are
stalled by DNA lesions, such as 1) pyrimidine
dimer, 2) polycyclic aromatic DNA adducts and 3)
abasic sites. Only Y family of DNA polymerases
are able to efficiently perform translesion DNA
synthesis.
2
(No Transcript)
3
Translesion DNA synthesis
Molecular Biology of the Gene, Fig. 9-18
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