Ocular Aberrations and Contrast Sensitivity in Eyes with AcrySof IQ SN60WF and AcrySof Natural SN60A

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Ocular Aberrations and Contrast Sensitivity in
Eyes with AcrySof IQ SN60WF and AcrySof Natural
SN60AT IOLs

• Shady T. Awwad, MD,
• Danny Lee, MD
• Surendar Dwarakanathan, MD
• R Wayne Bowman, MD
• H Dwight Cavanagh, MD, PhD
• James P. McCulley, MD
• The University of Texas Southwestern Medical
  Center at Dallas

None of the authors has financial interest in the
material discussed. JPM is a consultant in Alcon,
Inc
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Objectives

• To Determine whether an aspheric central
  posterior optic of an IOL effectively decreases
  spherical aberration and improves visual quality
  over conventional spheric optic design lenses

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Materials Methods

• Prospective non-randomized comparative study
• 52 eyes of 36 patients that underwent
  uncomplicated phacoemulsification with either
• Acrysof Natural SN60AT
• Acrysof IQ SN60WF
• Inclusion criteria
• No previous ocular diseases or surgeries
• Axial length between 22 and 28 mm
• BSCVA, refractive error and scotopic and mesopic
  pupil size were recorded.
• Contrast sensitivity was evaluated under
  Photopic, Mesopic, and dim Glare conditions
• Ocular higher order aberrations
• measured using the LADARWave aberrometer
• Scotopic pupils with optical zones of 4 mm and 6
  mm.
• When needed, one drop of 2.5 phenylephrine was
  used to dilate the pupils to beyond the 6.0 mm
  zone
• Centration, tilt, and clarity of the intraocular
  lens was assessed

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Results
Demographics
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Photopic Contrast Sensitivity
No statistical significance reached
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Results Contrast Sensitivity
Mesopic Contrast Sensitivity


Plt0.05
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Results Contrast Sensitivity Dim
Glare Contrast Sensitivity

Plt0.05
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Results Higher Order Aberrations
4 mm pupils


6 mm pupils


Plt0.05
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Ocular Higher Order Aberrationsat 4 mm Pupils
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Ocular Higher Order Aberrationsat 6 mm Pupils
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Conclusions

• Acrysof IQ does decrease spherical aberration
  with concomittant decrease in HOAs
• More so over large (nightime) pupils than smaller
  (daytime) pupils
• Acrysof IQ seems to provide better mesopic
  contrast sensitivity profile at high grating
  frequencies
• Both with or without glare
• Subclinical decentration and/or tilt of Acrysof
  IQ does not seem to affect coma levels as
  compared to Acrysof Natural
• The current study compared two identical IOLs
  except for the optic design (spheric vs aspheric)
• Advantage over other studies in the literature
• Studies using a larger sample of patients are
  needed to confirm and extend the results obtained